Synthesis of 1,3-Dioxin-4-ones and Their Use in Synthesis. XI. : 2,2-Dimethyl-1,3-dioxin-4-one as a Synthetic Equivalent of Formylketene : Synthesis of Heterocyclic Compounds

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概要

• 論文の詳細を見る

• Cycloaddition of formylketene generated in situ by thermolysis of 2,2-dimethyl-1,3-dioxin-4-one with N-benzhydrylidenebenzylamine yields 3-benzyl-2,2-diphenyl-1,3-oxazin-4-one. Analogous reactions with a carbodiimide, cyanamide, and keteneacetal afford the corresponding 4+2 cycloadducts. Reaction of formylketene with 3-amino-2-butenamides affords 4-hydroxy-2-pyridones having a C-2 unit at the 3-position.

• 公益社団法人日本薬学会の論文
• 1986-02-25

著者

• 佐藤 雅之

  静岡県立大学薬学部

• 金子 主税

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 金子 主税

  Pharmaceutical Institute Medical Faculty University Of Tokyo

• 佐藤 雅之

  Pharmaceutical Institute, Tohoku University

• 金子 主税

  Pharmaceutical Institute Tohoku University

• 米田 直樹

  Pharmaceutical Institute, Tohoku University

• 米田 直樹

  Pharmaceutical Institute Tohoku University

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