The Convenient Synthesis of 25-Hydroxycholesterol

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概要

• 論文の詳細を見る

• The convenient synthesis of 25-hydroxycholesterol (6) is described. 5β-Cholestan-3α, 25-diol (2) derived from lithocholic acid was converted to 6 via four steps : oxidationbromination, dehydrobromination, deconjugation, and reduction. The overall yield of 25-hydroxycholesterol (6) starting from 2 was ca. 50%.

• 公益社団法人日本薬学会の論文
• 1979-01-25

著者

• 金子 主税

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 新藤 実

  Research Laboratories, Chugai Pharmaceutical Co., Ltd.

• 新藤 実

  New Drug Research Laboratories Chugai Pharmaceutical Co. Ltd.

• 松永 功

  New Drug Research Laboratories Chugai Pharmaceutical Co. Ltd.

• 越智 清成

  Exploratory Research Laboratories, Chugai Pharmaceutical Co., Ltd.,

• 金子 主税

  Pharmaceutical Institute Tohoku University

• 越智 清成

  Exploratory Research Laboratories Chugai Pharmaceutical Co. Ltd.

• 松永 功

  New Drug Research Laboratories, Chugai Pharmaceutical Co., Ltd.,

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