Photolysis of 2-(Trifluoromethyl) quinoline 1-Oxides and 1-(Trifluoromethyl) isoquinoline 2-Oxide
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概要
- 論文の詳細を見る
Photolysis of a series of 2-(trifluoromethyl) quinoline 1-oxides (1a-d) in various solvent is reported. In contrast to the large solvent effects upon the product distribution as found in the photolysis of quinoline 1-oxide and its 2-alkylated derivatives, the photolysis of these four N-oxides shows no such solvent effects and results in the formation of the corresponding 3,1-benzoxazepines (IIa-d), irrespective of the kinds of solvents used for irradiation. Similarly, the photolysis of 1-(trifluoromethyl) isoquinoline 2-oxide (IV) is also found to give the corresponding 1,3-benzoxazepine (V) as a sole rearrangement product. A mechanistic rationalization of these photo-rearrangement reactions is presented.
- 公益社団法人日本薬学会の論文
- 1974-09-25
著者
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小林 義郎
Tokyo College of Pharmacy
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金子 主税
Faculty Of Pharmaceutical Sciences Kanazawa University
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林 純衣
Research Institute for Medical Engineering, Tokyo Medical and Dental University
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金子 主税
Pharmaceutical Institute Tohoku University
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林 純衣
Research Institute For Medical Engineering Tokyo Medical And Dental University
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