Studies on the Reactions of Heterocyclic Compounds. X. 1,3-Dipolar Cycloaddition Reaction of Isoquinolinium Ylides and Dicyanoacetylene
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概要
- 論文の詳細を見る
The 1,3-dipolar cycloaddition of dicyanoacetylene (IIb) to isoquinolinium ylides did not give the primary adduct but the aromatized and/or isomerized products. Further, in the reaction of isoquinolinium bis(methoxycarbonyl)methylide (Ia), possibly a rearranged addition product, 1,10b-dihydropyrrolo[2,1-α]isoquinoline (VII), was obtained beside 2,3-dihydropyrrolo[2,1-α]isoquinoline (Va) and pyrrolo[2,1-α]isoquinoline (VIa). In the reaction of isoquinolinium cyano(methoxycarbonyl)methylide (Ib), 2,3-dihydropyrrolo[2,1-α]isoquinoline (VIII), formed by the liberation of a methoxycarbonyl group, was obtained in addition to VIa and pyrrolo[2,1-α]isoquinoline-1,2,3-tricarbonitrile (VIb).
- 公益社団法人日本薬学会の論文
- 1973-05-25
著者
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小林 義郎
Tokyo College of Pharmacy
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関根 安男
Research Foundation Itsuu Laboratory
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熊懐 稜丸
Tokyo College of Pharmacy
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久津間 輝雄
Tokyo College of Pharmacy
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関根 安男
Tokyo College of Pharmacy
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久津間 輝雄
Tokyo College Of Pharmacy:(present Address) Research Laboratories Ohta Seiyaku Co. Ltd.
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