Studies on Organic Fluorine Compounds. IV. Conversion of Alcohols to Fluorides by Diphenyltrifluorophosphorane
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概要
- 論文の詳細を見る
The reactions of diphenyltrifluorophosphorane with alcohols were studied, and it was found to be a more excellent one-step fluorinating reagent for substituting the hydroxyl group of alcohols. Compared with difluorotriphenylphosphorane discussed in the previous paper, this reagent is superior in its being able to be produced at less cost and its reaction starting at the lower temperature. The reaction mechanism when solvent was used is presumed to be the same as in the case of difluorotriphenylphosphorane, but reaction modes differ when solvent was not used. To use solvent is better for preparing alkyl fluoride.
- 公益社団法人日本薬学会の論文
- 1968-09-25
著者
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小林 義郎
Tokyo College of Pharmacy
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明石 智元
Research Laboratories Yawata Chemical Industry Co. Ltd.
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森永 邦夫
Tokyo College of Pharmacy
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森永 邦夫
(Present address)Shizuoka College of Pharmacy
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