Studies on the Reactions of Heterocyclic Compounds. XIII. Basicity of 1,6-Naphthyridine and Its N-Oxides : Correlation to Peracid Oxidation
スポンサーリンク
概要
- 論文の詳細を見る
Selective protonation of 1,6-naphthyridine and its N-oxides was studied from the results of ultraviolet spectra in various concentrations of sulfuric acid. Nitrogen atom in 6-position was protonated preferentially to that in 1-position, which seems to be caused by the stability of 2,6-quinonoid structure. This point is also supported by the difference in the changes of effective nuclear charges on protonation, which are calculated by SCF-LCAO-MO method. It was also shown that protonation plays an important role in N-oxidation of some heteroaromatic amines with a peracid.
- 公益社団法人日本薬学会の論文
- 1974-12-25
著者
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小林 義郎
Tokyo College of Pharmacy
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佐藤 治男
Sato Institute Of Pharmaceutical Sciences
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熊懐 稜丸
Tokyo College of Pharmacy
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佐藤 治男
Tokyo College of Pharmacy
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