A NOVEL THREE-CARBON ANNELATION METHOD FOR PYRIDINE DERIVATIVES

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概要

• 論文の詳細を見る

• Cyclopentane ring annelation methods for 2-pyridone derivatives are provided by cyclobutane ring expansion of 1,2-dihydrocyclobuta [c] pyridin-3 (4H)-ones having an appropriate function at the l-position. Since the latter compounds are readily accessible from 4-alkoxy-2-pyridones via our two-step procedure (Kaneko-Naito method), the methods seem to have wide applicability for the synthesis of cyclopenta [c] pyridines.

• 公益社団法人日本薬学会の論文
• 1983-06-25

著者

• 大橋 徹生

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 金子 主税

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 下村 直之

  Tsukuba Research Laboratories, Eisai Co., Ltd.,

• 染井 正徳

  Faculty of Parmaceutical Sciences, Kanazawa University

• 下村 直之

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 百瀬 祐

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 内藤 俊彦

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 下村 直之

  Tsukuba Research Laboratories Eisai Co. Ltd.

• 百瀬 祐

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 金子 主税

  Pharmaceutical Institute Tohoku University

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