The Chemistry of Indoles. XII. A Facile Route to 5-Nitroisocoumarins and Methyl Indole-4-carboxylate

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概要

• 論文の詳細を見る

• A convenient synthesis of 5-substituted isocoumarin derivatives, such as 5-nitroisocoumarin (2), 5-aminoisocoumarin (8), 3,4-dihydro-3-methoxy-5-nitroisocoumarin (3), and 5-amino-3,4-dihydro-3-methoxyisocoumarin (10), from 2-methyl-3-nitrobenzoic acid (1) is reported. Several synthetic routes to methyl indole-4-carboxylate (9) from methyl 2-methyl-3-nitrobenzoate (4) directly or via these isocoumarins (8 and 10) are also presented.

• 公益社団法人日本薬学会の論文
• 1981-01-25

著者

• 金子 主税

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 染井 正徳

  Faculty of Parmaceutical Sciences, Kanazawa University

• 金子 主税

  Pharmaceutical Institute Tohoku University

• 唐沢 良夫

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 庄田 敏哉

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 庄田 敏哉

  Faculty Of Pharmaceutical Sciences Kanazawa University

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