The Chemistry of Indoles. XXXII. : A Facile Synthetic Method for 6-Indolecarbaldehyde, 6-Indolemethanol, and 6-Substituted 1-Hydroxyindoles and Its Application for the Synthesis of a Natural Alkaloid, (E)-6-(3-Methylbuta-1,3-dienyl)indole
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概要
- 論文の詳細を見る
Trivalent titanium ion can reduce arylaldehydes, and the reaction is controllable by selecting the pH of the reaction medium. Utilizing this new finding, 6-indolecarbaldehyde and 6-indolemethanol were convenienthy produced by the modified Leimgruber-Batcho method with titanium(III) chloride as the reducing agent. Syntheses of a natural alkaloid, (E)-6-(3-methylbuta-1,3-dienyl)indole, and some new 6-substituted 1-hydroxyindoles are also reported.
- 1986-10-25
著者
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染井 正徳
Faculty of Parmaceutical Sciences, Kanazawa University
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染井 正徳
Faculty Of Pharmaceutical Sciences Kanazawa University
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