THE CHEMISTRY OF 1-HYDROXYINDOLES : SYNTHESES OF METHYL 1-HYDROXYINDOLE-3-ACETATE, N__-B-ACETYL-1-HYDROXY-TRYPTAMINE, (±)- AND (S__-)-1-HYDROXYTRYPTOPHAN DERIVATIVES

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概要

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• Methyl 1-hydroxyindole-3-acetate, (±)-2-acetoamino-3-(10hydroxyindol-3-yl)propanol, N__-b-acetyl-1-hydroxytryptamine, (±)- and (S__-)-(+)-N__-b-acetyl-1-hydroxytryptophan methyl ester, which are needed for inspecting our hypothesis regarding the metabolism of tryptophan, were prepared for the first time. The structural proof of (±)-N__-b-acetyl-1-hydroxytryptophan methyl ester by X-ray crysatllographic analysis is also reported.

• 1991-07-25

著者

• 染井 正徳

  Faculty of Parmaceutical Sciences, Kanazawa University

• 清水 和久

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 太田 敏春

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 福井 喜一

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 川崎 俊哉

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 川崎 俊哉

  Faculty Of Pharmaceutical Sciences Kanazawa University

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