光化学的周辺環状反応を用いる生理活性化合物の合成

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概要

• 論文の詳細を見る

• Novel Synthetic approaches to β-lactams and Corey lactone analogues via four-membered ring intermediates formed by photochemical pericyclic reaction, followed by subsequent retro-aldol-type C-C bond fission are described. The same approach to carbocyclic C-nucleosides which involves thermal 4 + 2 addition reaction in the first step is also reported. These examples demonstrate that pericyclic reactions, if combined with C-C bond fission of the carbocyclic rings thus formed, provide productive synthetic methods of biologically active substances which allow strict regio-and stereochemical control of the required functionality of the target molecules.

• 社団法人 有機合成化学協会の論文

著者

• 佐藤 雅之

  静岡県立大学薬学部

• 金子 主税

  東北大学

• 金子 主税

  東北大学薬学部

• 佐藤 雅之

  東北大学薬学部

• 片桐 信弥

  Health Sci. Univ. Hokkaido Hokkaido Jpn

• 片桐 信弥

  Pharmaceutical Institute Tohoku University

• 片桐 信弥

  東北大学薬学部

• 金子 主税

  東北大学薬学部薬化学教室

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