Novel Annelation Method to Pyridine and Isoquinoline by Photochemical Means

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概要

• 論文の詳細を見る

• Intramolecular photoaddition reactions of 2-(ω-alkenyl)isoquinolin-1(2H)-ones and 1-(ω-alkenyl)pyridin-2(1H)-ones were examined, and the regioselectivity and dependence of these reactions on the length of methylene chain in the alkenyl group were clarified. By utilizing these reactions, a synthetic route to indolizine and quinolizine derivatives was elaborated. By an extension of this approach to the intermolecular reaction, 6-methoxy-3-methyl-1,2-dihydrocyclobuta[b]pyridin-4(3H)-one was synthesized from 4,6-dimethoxy-1-methylpyridin-2(1H)-one.

• 公益社団法人日本薬学会の論文
• 1986-09-25

著者

• 佐藤 雅之

  静岡県立大学薬学部

• 金子 主税

  東北大学

• 金子 主税

  Pharmaceutical Institute Medical Faculty University Of Tokyo

• 佐藤 雅之

  Pharmaceutical Institute, Tohoku University

• 片桐 信弥

  Pharmaceutical Institute, Tohoku University

• 片桐 信弥

  Health Sci. Univ. Hokkaido Hokkaido Jpn

• 片桐 信弥

  Pharmaceutical Institute Tohoku University

• 内山 景志

  Pharmaceutical Institute Tohoku University

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