Synthesis of 1,3-Dioxin-4-one Derivatives

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概要

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• A facile and general synthesis of 2,2-dimethyl-1,3-dioxin-4-one derivatives (1) is reported. Treatment of β-keto acids with a mixture of acetone, acetic anhydride, and conc. sulfuric acid or with a mixture of isopropenyl acetate and conc. sulfuric acid gave 2,2-dimethyl-1,3-dioxin-4-ones (1). Similar treatment of tert-butyl esters of β-keto acids also gave 1.

• 公益社団法人日本薬学会の論文
• 1983-06-25

著者

• 佐藤 雅之

  静岡県立大学薬学部

• 佐藤 雅之

  Pharmaceutical Institute, Tohoku University

• 加藤 鐵三

  Central Research Institute Mect Corporation

• 加藤 鐵三

  Pharmaceutical Institute. Tohoku University

• 小笠原 弘道

  Pharmaceutical Institute, Tohoku University

• 小笠原 弘道

  Pharmaceutical Institute Tohoku University

• 大井 慶一

  Pharmaceutical Institute, Tohoku University Aobayama

• 大井 慶一

  Pharmaceutical Institute Tohoku University Aobayama

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