ケテンおよびその誘導体の研究(第52報)ジケテンとα(β)-アミノニトリルとの反応
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概要
- 論文の詳細を見る
Reaction of diketene with α-aminonitrile and β-aminonitrile afforded their N-acetoacetate (VI, VII) in a good yield. VI was easily cyclized with triethylamine or sodium methoxide giving 3-acetyl-4-amino-3-pyrrolin-2-one (VIII), while treatment of VII with sodium methoxide gave 1-substituted 3-acetyl-4-amino-5,6-dihydro-2(1H)-pyridone (X) and 1-substituted 4-methyl-1,2-5,6-tetrahydro-6-oxonicotinonitrile (XI).
- 公益社団法人日本薬学会の論文
- 1972-12-25
著者
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佐藤 雅之
静岡県立大学薬学部
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加藤 鉄三
東北大学 薬
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加藤 鉄三
東北大学薬学部
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佐藤 雅之
東北大学薬学部
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加藤 鉄三
Pharmaceutical Institute. Tohoku University
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