Studies on Ketene and Its Derivatives. CII. Reaction of Diketene with Cyanamide Derivatives
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概要
- 論文の詳細を見る
The reaction of diketene with cyanamide gave 2-amino-6-methyl-4H-1,3-oxazin-4-one, which was transformed to 6-methyluracil by refluxing it in acetic acid. Diketene also reacted with monosubstituted cyanamides to give 1,3-oxazin-4-one derivatives, which could be similarly converted into 1-substituted 6-methyluracils. The reaction of diketene with dicyanodiamide afforded 2-guanidino-6-methyl-4H-1,3-oxazin-4-one, which, on treatment with ammonia, afforded 2-guanidino-4-hydroxy-6-methylpyrimidine.
- 社団法人日本薬学会の論文
- 1981-03-25
著者
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千葉 卓男
Pharmaceutical Institute, Tohoku University
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千葉 卓男
Pharmaceutical Institute Tohoku University
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加藤 鉄三
東北大学 薬
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加藤 鉄三
Pharmaceutical Institute Tohoku University
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高橋 仁
Pharmaceutical Institute, Tohoku University
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清水 猛
Pharmaceutical Institute, Tohoku University
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清水 猛
Pharmaceutical Institute Tohoku University
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高橋 仁
Pharmaceutical Institute Tohoku University
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加藤 鉄三
Pharmaceutical Institute. Tohoku University
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