ケテンおよびその誘導体の研究(第99報)ジケテンとイソキノリンとの反応(補遺)
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概要
- 論文の詳細を見る
The reaction of isoquinoline with diketene in benzene at reflux affords 13,13a-dihydro-11-methyl-8H, 9H-8,9-dioxobenzo [α] pyrano [3,2-α] quinolizine (2a) in a 40% yield. When the reaction is carried out at room temperature, compound 2a and 13,13a-dihydro-9-methyl-8H, 11H-8,11-dioxobenzo [α] pyrano [3,2-g] quinolizine (3) are obtained in 3% and 30% yields, respectively. Compound 3 is oxidized with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) to give 9-methyl-8H, 11H-8,11-dioxobenzo [α] pyrano [3,2-g] quinolizine (4) in an 85% yield.
- 社団法人日本薬学会の論文
- 1980-05-25
著者
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佐々木 俊樹
東北大学薬学部
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千葉 卓男
Pharmaceutical Institute Tohoku University
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加藤 鉄三
東北大学 薬
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加藤 鉄三
東北大学薬学部
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千葉 卓男
東北大学薬学部
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白石 隆幸
東北大学薬学部
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加藤 鉄三
Pharmaceutical Institute. Tohoku University
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