Keteneおよびその誘導体の研究(第44報) : β-AminocinnamonitrileとEthyl Acetoacetateとから得られるピリドン誘導体の構造について
スポンサーリンク
概要
- 論文の詳細を見る
The structure of 2-phenyl-3-cyano-6-methyl-4-pyridinol (III), proposed by von Meyer in 1908 for the crystalline product of mp 244° obtained by the reaction of β-aminocinnamonitrile (I) with ethyl acetoacetate, is pointed out as an error and the correct structure for it proposed as 4-methyl-5-cyano-6-phenyl-2-pyridinone (IV). The compound corresponding to III is obtained by the reaction of I with diketene.
- 公益社団法人日本薬学会の論文
- 1971-07-25
著者
-
加藤 鉄三
東北大学医学部薬学科
-
山中 宏
東北大学医学部薬学科
-
穂積 豊治
東北大学薬学部
-
加藤 鉄三
Pharmaceutical Institute. Tohoku University
-
穂積 豊治
東北大学医学部薬学科
関連論文
- Photoaddition of 2-Quinolone and 2-Pyridone Derivatives to Diketene : On the Regioselectivity of the Photoaddition
- Studies on Ketene and Its Derivatives. XCV. Reaction of Diketene with Acyl Azides
- 1,3-Oxazine化学の最近の進歩 (ヘテロ環の化学-5-)
- Synthesis of Methylpyridine Derivatives. XXX. Reaction of Active Methylene Compounds with 6-Methyl-2-phenyl-4H-1,3-oxazin-4-one and 2-Ethoxy-2,6-dimethyl-2H-1,3-oxazin-4 (3H)-one to give 3-Acetylpyridone Derivatives
- Keteneおよびその誘導体の研究(第65報)KeteneとKetene Acetalとの反応
- Keteneおよびその誘導体の研究(第61報)第一アミンとChloroketene Diethylacetalとの反応
- Keteneおよびその誘導体の研究(第59報)5-Acetyl-2,6-dimethyl-4(3H)-pyrimidoneの閉環反応
- Studies on Ketene and Its Derivatives. LVII. Reaction of Diketene with β-Diketones
- Keteneおよびその誘導体の研究(第55報)第一アミンとKetene Acetalとの反応
- Studies on Ketene and Its Derivatives. LIV. Reaction of Diketene with Ketene Acetals
- ケテンおよびその誘導体の研究(第50報)脂肪族イミドエステルとジケテンとの反応
- Keteneおよびその誘導体の研究(第42報) : 1-Acetoacetylaziridine誘導体の環拡大反応
- Keteneおよびその誘導体の研究(第40報) : N-Ethylideneisopropylamine, N-Methylenecyclohexylamine, およびN-Methylene-tert-butylamineとDiketeneとの反応
- ケテンおよびその誘導体の研究(第37報) : Ketone Anilおよび関連化合物とジケテンとの反応
- Keteneおよびその誘導体の研究(第16報) : Schiff BaseとDiketeneとの反応
- Reaction of Ethyl 4-Bromoacetoacetate with Carbon Disulfide and Active Methylene Compounds
- Neighboring Group Participation of the N-Oxide Group in the Reaction of Methyl 1-Oxido-2-pyridyl Ketone Oxime with Tosyl Chloride
- Reaction of 4-Haloacetoacetate with Phenols in the Presence of Aluminum Chloride
- Studies on Ketene and Its Derivatives. CVII. Photoreaction of Diketene with 6-Methyluracil
- Studies on Ketene and Its Derivatives. CVI. Photoreaction of Diketene with N-Phenylmaleimide and Dimethyl-N-phenylmaleimide
- Studies on Ketene and Its Derivatives. CII. Reaction of Diketene with Cyanamide Derivatives
- アセトアセトアミド誘導体を用いたBiginelli反応
- ケテンおよびその誘導体の研究(第104報)3-アミノクロトンアミド誘導体とジケテンとの反応
- ケテンおよびその誘導体の研究(第99報)ジケテンとイソキノリンとの反応(補遺)
- Studies on Ketene and Its Derivatives. XCVII. Photoreactions of Diketene with Maleic Anhydride and Dimethylmaleic Anhydride
- Isoquinolinium MethylidesとKetone類との反応
- Studies on Ketene and Its Derivatives. XCVI. Synthesis of Pyrido [2,1-b] benzoazoles
- Reaction of Ethyl Acetoacetate with Isoquinolinium and Pyridinium Ylides
- Synthesis of Methylpyridine Derivatives. XXXII. Reaction of Pyridine, Quinoline, and Isoquinoline with 4-Bromoacetoacetic Acid Derivatives and Synthesis of Indolizine Derivatives
- Reaction of Diazomethane with 2-Acetyl-5,5-diphenyl-2,4-pentadienoic Acid and Related Compounds
- Studies on Ketene and Its Derivatives. LXXXIV. Reaction of Diketene with Tetrazole Derivatives
- Studies on Ketene and Its Derivatives. LXXV. Reaction of Diketene with N-Benzylacetimidate and Lactim Ethers to give 1,6-Naphthyridine Derivatives
- Reaction of β-Aminocrotonamide with N-Acylated Amino Acid Esters to give 2-Acylaminoalkyl-6-methylpyrimidin-4 (3H)-ones and Their Ring Closure with Polyphosphoric Acid (PPA)
- Ring Transformation of 5-Oxo-4-oxaspiro [2.3] hexanes
- Studies on Ketene and Its Derivatives. XCIV. Reaction of Diketene with Diazoacetone and 2-Diazoesters
- ドクササコの有毒成分とその薬理作用
- Chemical Reactions of Bikaverin
- Studies on Ketene and Its Derivatives. LIII. Reaction of Diketene with Diazoacetophenone and Ethyl Diazoacetate
- Studies on Ketene and Its Derivatives. XLVIII. Reaction of Diketene with Hydroxylamine
- Studies on Ketene and Its Derivatives. XLVII. Reaction of 2-Aminopyridine with Diketene
- Studies on Ketene and Its Derivatives. XLVI. Mass Spectrometric Studies of 3-Acetyl-4-hydroxy-6-methyl-1-pyridyl-2-pyridones and N-Pyridyl-2,6-dimethyl-4-pyrone-3-carboxamides
- キノリン誘導体の塩素化反応
- Methylpyridine誘導体の合成(第29報)Methylpyridineおよび同族体のAryl化反応
- Studies on Ketene and Its Derivatives. LX. Reaction of Diketene with Quinoline 1-Oxide (Supplement)
- Synthesis of Methylpyridine Derivatives. XXVII. Synthesis of 1,3-Disubstituted-4-oxo-quinolizine and 2,4-Disubstituted-1-oxo-benzo [c] quinolizine Derivatives
- ケテンおよびその誘導体の研究(第58報)3-Aminocrotonamideとα, β-不飽和カルボン酸エステル類との反応
- Keteneおよびその誘導体の研究(第56報)Pyrrolidylidene誘導体とDiketeneによる5-Methyl-8-substituted-1,2,3,7-tetrahydroindolizine-7-oneの合成
- Studies on Ketene and Its Derivatives. XLIX. Reaction of Diketene with β-Ketoesters to give Ethyl Orsellinate, Divarate, Olivetol Carboxylate, and Sphaeropherol Carboxylate
- Keteneおよびその誘導体の研究(第45報) : 2-Alkyl-2-imidazolineとDiketeneとの反応
- 3-Amino-4-methyl-2-pentenamide, 2-Amino-1-cyclohexene-1-carboxamideおよび3-Amino-2,4-diphenyl-2-butenamideの合成ならびにそれらを用いた4(3H)-Pyrimidone誘導体の合成
- Synthesis of N-Acylacetoacetamide using 2,2,6-Trimethyl-1,3-dioxin-4-one
- Studies on Ketene and Its Derivatives. CV. Photoreaction of Diketene with sec-Alcohols
- Synthesis of Methylpyridine Derivatives. XXXIV. Condensation of Acetoacetamide with Ketones to form Pyridone Derivatives
- Studies on Ketene and Its Derivatives. XCII. Reaction of Diketene with Benzaldehyde, Cinnamaldehyde, and β-Phenylcinnamaldehyde
- Studies on Ketene and Its Derivatives. LXXXVII. Photoreaction of Diketene with 3-Acetoxy-5,5-dimethyl-2-cyclohexenone
- Studies on Ketene and Its Derivatives. LXIX. Reaction of Diketene with Hydrazobenzenes
- Studies on Ketene and Its Derivatives. LXVII. Photoreaction of Benzophenone and Benzaldehyde with Diketene
- ケテンおよびその誘導体の研究(第52報)ジケテンとα(β)-アミノニトリルとの反応
- ケテンおよびその誘導体の研究(第51報))α-アミノ酸アミドとジケテンとの反応
- Studies on Ketene and Its Derivatives. XLI. Reaction of α-Aminoketone with Diketene
- アセトンジカルボン酸と無水酢酸との反応(第2報)
- Keteneおよびその誘導体の研究(第34報) : Diketeneとウレタンおよび酸アミドとの反応
- Keteneおよびその誘導体の研究(第30報) : Diketeneとアンモニアおよび脂肪族アミンとの反応
- Keteneおよびその誘導体の研究(第23報) : Diketeneとα-アミノ酸との反応
- Keteneおよびその誘導体の研究(第22報) : Diketeneとアニリン誘導体との反応
- Studies on Ketene and Its Derivatives. XXVIII. Reaction of β-Aminocrotonamide with Ketene and Diketene
- ケテンおよびその誘導体の研究(第36報) : Acetoacetamideおよびβ-Aminocrotonamideとアルデヒドとの反応
- Keteneおよびその誘導体の研究(第14報) : Diethyl2,5-dihydroxyterephthalateの合成
- Keteneおよびその誘導体の研究(第15報) : Quinoline-Diketene付加体とAmmoniaとの反応成績体
- ジケテンのエキソメチレンニ重結合の新しい付加反応
- メチルピリジン誘導体の合成(第24報) : Methyl Pyridyl Ketone Oximeおよびそれらの1-OxideのBeckmann転位
- メチルピリジン誘導体の合成(第25報) : α-置換-2-pyridineacetonitrile誘導体の合成
- Synthesis of 1-Substituted-1,2,5,6-tetrahydro-4H-pyrrolo (3,2,1-ij) quinolin-2-one
- Studies on Ketene and Its Derivatives. XXXIX. Reaction of Diketene with Semicarbazone
- Studies on Ketene and Its Derivatives. XXXVIII. Reaction of Diketene with Phenylhydrazones to give 4-Acetyl-2-phenylpyrazolidin-3-ones
- Keteneおよびその誘導体の研究(第44報) : β-AminocinnamonitrileとEthyl Acetoacetateとから得られるピリドン誘導体の構造について
- ケテンおよびその誘導体の研究(第43報) : Primary EnamineとKeteneまたはDiketeneとの反応
- ケテンおよびその誘導体の研究(第20報) : Diketeneと2-Pyridylacetonitrileとの反応
- Studies on the Synthesis of Indole Related Compounds. II. Diels-Alder Reaction of Phenacylidene Indolinone
- Indole関連化合物の合成研究(第1報) : 3-Acetyl-2-indolinone
- メチルピリミジン誘導体と亜硝酸イソアミルとの反応
- メチルピリミジン誘導体のVilsmeier反応
- N-Oxidation of 4-Chloropyrimidine Derivatives
- Studies on Ketene and Its Derivatives. XXXII. Reactions of α, β-Unsaturated Acid Anhydride with β-Aminocrotonamide and Related Compounds
- ケテンおよびその誘導体の研究(第33報) : Ethyl 3-Aminocrotonateのアセチル化反応
- Keteneおよびその誘導体の研究(第27報) : β-Aminocrotonamideのアシル化および閉環反応
- Studies on Ketene and Its Derivatives. XXVI. The Structure of the Self-condensation Product of Acetoacetamide (Supplement)
- Keteneおよびその誘導体の研究(第25報) : 3-Acetyl-4-hydroxy-6-methyl-1H-2-pyridone OximeおよびDehydroacetic Acid Oximeの閉環反応
- ケテンおよびその誘導体の研究(第35報) : β-Aminocrotonamideとカルボン酸エステルとによる2-置換-6-メチルピリミドンの合成法
- ピリミジン誘導体の N-オキシド化反応
- ケテンおよびその誘導体の研究(第19報) : 2-アルキル(アリル)置換-6-メチル-4-ピリミドンの新合成法
- Keteneおよびその誘導体の研究(第29報) : Quinolizine誘導体の合成
- ジケテン
- Keteneおよびその誘導体の研究(第24報) : DiketeneとKetimineとの反応
- メチルピリジン誘導体の合成(第23報) : 2,6-Lutidine誘導体のクロル化反応
- Methylpyrimidine誘導体のクロル化反応
- Studies on Ketene and Its Derivatives. XXXI. 2-Acetonyloxazolines