ケテンおよびその誘導体の研究(第33報) : Ethyl 3-Aminocrotonateのアセチル化反応
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概要
- 論文の詳細を見る
Acetylation of ethyl 3-aminocrotonate (I) gives three kinds of monoacetate according to the kind of acetylation agent used. The product of mp 54° is a C-acetate (V) which is obtained in a good yield from I and ketene. The isomer (II) of mp 63° obtained by the treatment of I with acetic anhydride is an N-acetate of I, while the other isomer (III) of mp 108° obtained by the treatment of I with acetyl chloride in pyridine is also an N-acetate of I. II and III are considered to be cis-trans isomers with respect to the enamine carbon-carbon double bond. The structure of II, III, and V is not inconsistent with the result of their decomposition reaction and instrumental analyses.
- 公益社団法人日本薬学会の論文
- 1969-12-25
著者
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加藤 鉄三
東北大学医学部薬学科
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山中 宏
東北大学医学部薬学科
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加藤 鉄三
Pharmaceutical Institute. Tohoku University
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川又 淳司
Pharmaceutical Institute Tohoku University
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川又 淳司
東北大学医学部薬学科
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