Studies on Ketene and Its Derivatives. XCVI. Synthesis of Pyrido [2,1-b] benzoazoles
スポンサーリンク
概要
- 論文の詳細を見る
Vilsmeier reactions of ethyl 2-benzimidazoleacetate (4), ethyl 2-benzothiazoleacetate (5), and ethyl 2-benzoxazoleacetate (6) gave ethyl α-(dimethylaminomethylene)-2-benzimidazoleacetate (7), ethyl α-(dimethylaminomethylene)-2-benzothiazoleacetate (8), and ethyl α-(dimethylaminomethylene)-2-benzoxazoleacetate (9), respectively. Reaction of the enamines (7,8 and 9) with diketene, acetic anhydride, propionic anhydride, and active methylene compounds such as ethyl cyanoacetate and malononitrile gave rise to the corresponding pyrido [2,1-b] benzoazoles (10-19).
- 社団法人日本薬学会の論文
- 1979-05-25
著者
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千葉 卓男
Pharmaceutical Institute, Tohoku University
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千葉 卓男
Pharmaceutical Institute Tohoku University
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加藤 鉄三
東北大学 薬
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加藤 鉄三
Pharmaceutical Institute Tohoku University
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岡田 次雄
Pharmaceutical Institute, Tohoku University
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加藤 鉄三
Pharmaceutical Institute. Tohoku University
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岡田 次雄
Pharmaceutical Institute Tohoku University
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