Studies on Ketene and Its Derivatives. LIII. Reaction of Diketene with Diazoacetophenone and Ethyl Diazoacetate
スポンサーリンク
概要
- 論文の詳細を見る
Diketene reacted with diazoacetophenone (Ia) to give two isomeric spiro compounds, 2-(trans-2-benzoyl-1-hydroxycyclopropane)-acetic acid β-lactone (IIa) and 2-(cis-2-benzoyl-1-hydroxycyclopropane)-acetic acid β-lactone (IIa'). Similarly, p-methoxy-α-diazoacetophenone (Ib) was transformed to 2-[trans-2-(p-methoxybenzoyl)-1-bydroxycyclopropane]-acetic acid β-lactone (IIb) and 2-[cis-2-(p-methoxybenzoyl)-1-hydroxycyclopropane]-acetic acid β-lactone (IIb'). Reaction of diketene with ethyl diazoacetate (Ic) gave furanone derivatives, 2,5-dihydro-2-ethoxycarbonyl-3-methylfuran-5-one (VII) and 2,5-dihydro-4-ethoxycarbonyl-methylfuran-2-one (VIII), together with 2-(trans-2-ethoxycarbonyl-1-hydroxycyclo-propane) acetic acid β-lactone (IIc).
- 公益社団法人日本薬学会の論文
- 1973-04-25
著者
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加藤 鉄三
東北大学 薬
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加藤 鉄三
Pharmaceutical Institute Tohoku University
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片桐 信弥
Pharmaceutical Institute, Tohoku University
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片桐 信弥
Health Sci. Univ. Hokkaido Hokkaido Jpn
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片桐 信弥
Pharmaceutical Institute Tohoku University
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加藤 鉄三
Pharmaceutical Institute. Tohoku University
関連論文
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- Studies on Ketene and Its Derivatives. XCV. Reaction of Diketene with Acyl Azides
- Synthesis of dl-Dehydroiridodiol
- Studies on Ketene and Its Derivatives. CI. Reaction of Diketene with 4-Amino-methylpyridine 1-Oxides
- Synthesis of Dihydrojasmone and cis-Jasmone
- Reaction of Ethyl 4-Halo-3-oxobutanoate with Diethyl Malonate, Methyl Cyanoacetate, and Malononitrile
- Studies on Ketene and Its Derivatives. LXXXV. Reactions of 4-Bromo-3-hydroxybutanoate and Its Acyl Derivatives
- 1,3-Oxazine化学の最近の進歩 (ヘテロ環の化学-5-)
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- Keteneおよびその誘導体の研究(第65報)KeteneとKetene Acetalとの反応
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- Studies on Ketene and Its Derivatives. LVII. Reaction of Diketene with β-Diketones
- Keteneおよびその誘導体の研究(第55報)第一アミンとKetene Acetalとの反応
- Studies on Ketene and Its Derivatives. LIV. Reaction of Diketene with Ketene Acetals
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- Studies on Ketene and Its Derivatives. XVIII. Reaction of Diketene with Acridine.
- Studies on Ketene and Its Derivatives. XVII. Reaction of Diketene with Imidates.
- Studies on Ketene and Its Derivatives. XI. Reaction of Diketene with Phenanthridine
- Studies on Ketene and its Derivatives. X. Reaction of Diketene with Schiff Base
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- Neighboring Group Participation of the N-Oxide Group in the Reaction of Methyl 1-Oxido-2-pyridyl Ketone Oxime with Tosyl Chloride
- Reaction of 4-Haloacetoacetate with Phenols in the Presence of Aluminum Chloride
- Studies on Ketene and Its Derivatives. CVII. Photoreaction of Diketene with 6-Methyluracil
- Studies on Ketene and Its Derivatives. CVI. Photoreaction of Diketene with N-Phenylmaleimide and Dimethyl-N-phenylmaleimide
- Studies on Ketene and Its Derivatives. CII. Reaction of Diketene with Cyanamide Derivatives
- アセトアセトアミド誘導体を用いたBiginelli反応
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- ジケテンのエキソメチレン二重結合の新しい付加反応
- ケテンおよびその誘導体の研究(第99報)ジケテンとイソキノリンとの反応(補遺)
- Studies on Ketene and Its Derivatives. XCVII. Photoreactions of Diketene with Maleic Anhydride and Dimethylmaleic Anhydride
- Isoquinolinium MethylidesとKetone類との反応
- Studies on Ketene and Its Derivatives. XCVI. Synthesis of Pyrido [2,1-b] benzoazoles
- Reaction of Ethyl Acetoacetate with Isoquinolinium and Pyridinium Ylides
- Synthesis of Methylpyridine Derivatives. XXXII. Reaction of Pyridine, Quinoline, and Isoquinoline with 4-Bromoacetoacetic Acid Derivatives and Synthesis of Indolizine Derivatives
- Reaction of Diazomethane with 2-Acetyl-5,5-diphenyl-2,4-pentadienoic Acid and Related Compounds
- Studies on Ketene and Its Derivatives. LXXXIV. Reaction of Diketene with Tetrazole Derivatives
- Studies on Ketene and Its Derivatives. LXXVII. Reaction of Diketene with Pyridineformimidates and Related Compounds to give 1,3-Oxazin-4-one Derivatives
- Studies on Ketene and Its Derivatives. LXXV. Reaction of Diketene with N-Benzylacetimidate and Lactim Ethers to give 1,6-Naphthyridine Derivatives
- Reaction of β-Aminocrotonamide with N-Acylated Amino Acid Esters to give 2-Acylaminoalkyl-6-methylpyrimidin-4 (3H)-ones and Their Ring Closure with Polyphosphoric Acid (PPA)
- Ring Transformation of 5-Oxo-4-oxaspiro [2.3] hexanes
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- ドクササコの有毒成分とその薬理作用
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- Studies on Ketene and Its Derivatives. XLVII. Reaction of 2-Aminopyridine with Diketene
- Studies on Ketene and Its Derivatives. XLVI. Mass Spectrometric Studies of 3-Acetyl-4-hydroxy-6-methyl-1-pyridyl-2-pyridones and N-Pyridyl-2,6-dimethyl-4-pyrone-3-carboxamides
- キノリン誘導体の塩素化反応
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- Studies on Ketene and Its Derivatives. LX. Reaction of Diketene with Quinoline 1-Oxide (Supplement)
- Synthesis of Methylpyridine Derivatives. XXVII. Synthesis of 1,3-Disubstituted-4-oxo-quinolizine and 2,4-Disubstituted-1-oxo-benzo [c] quinolizine Derivatives
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- Studies on Ketene and Its Derivatives. XLIX. Reaction of Diketene with β-Ketoesters to give Ethyl Orsellinate, Divarate, Olivetol Carboxylate, and Sphaeropherol Carboxylate
- Keteneおよびその誘導体の研究(第45報) : 2-Alkyl-2-imidazolineとDiketeneとの反応
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- Studies on Ketene and Its Derivatives. CV. Photoreaction of Diketene with sec-Alcohols
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- Studies on Ketene and Its Derivatives. XCII. Reaction of Diketene with Benzaldehyde, Cinnamaldehyde, and β-Phenylcinnamaldehyde
- Studies on Ketene and Its Derivatives. LXXXVII. Photoreaction of Diketene with 3-Acetoxy-5,5-dimethyl-2-cyclohexenone
- Studies on Ketene and Its Derivatives. LXIX. Reaction of Diketene with Hydrazobenzenes
- Studies on Ketene and Its Derivatives. LXVII. Photoreaction of Benzophenone and Benzaldehyde with Diketene
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- ケテンおよびその誘導体の研究(第51報))α-アミノ酸アミドとジケテンとの反応
- Studies on Ketene and Its Derivatives. XLI. Reaction of α-Aminoketone with Diketene
- Structure of the Product from the Reaction of Acetonedicarboxylic Acid with Acetic Anhydride
- Studies on Ketene and its Derivatives. VI. Reaction of Diketene with Aminopyridines and their N-Oxides
- Studies on Ketene and Its Derivatives. XXVIII. Reaction of β-Aminocrotonamide with Ketene and Diketene
- ジケテンのエキソメチレンニ重結合の新しい付加反応
- Reaction of Methyl 1-Oxido-2-pyridyl Ketone Oxime with Acetic Anhydride : Formation of a 3-Methylisoxazolo[4,5-b]pyridine Derivative(Organic,Chemical)
- Reaction of γ-Bromoacetoacetyl Compounds with Benzamide Oxime Derivatives : Synthesis of 4H-1,2,4-Oxadiazine Derivatives
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- Organic Sulfites containing a 1,2-Oxazine Ring
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- Studies on Ketene and Its Derivatives. LXXIX. Reaction of Diketene with Benzimidazole and 2-Methylbenzimidazole Derivatives
- Studies on Ketene and Its Derivatives. LXXXII. Reaction of Diketene with N-Phenylhydroxylamine Derivatives
- Studies on Ketene and Its Derivatives. LXXXI. Reaction of β-Aminocrotonamide with α, β-Unsaturated Ketones
- Studies on Ketene and Its Derivatives. LXXVI. Reactions of Acetoacetamide and β-Aminocrotonamide with β-Diketone, β-Ketoaldehyde and Related Compounds
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- Studies on Ketene and Its Derivatives. LXVI. Reaction of Acetoacetamide with α, β-Unsaturated Esters
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- Synthesis of Methylpyridine Derivatives. XVI. The Reaction of Picolines and their N-Oxides with Amyl Nitrite.
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- Synthesis of Methylpyridine Derivatives (XXI). Amination of Chloro-2,6-lutidines and Their N-Oxides via a Hetaryne Mechanism
- N-Oxidation of 4-Chloropyrimidine Derivatives
- Studies on Ketene and Its Derivatives. XXXII. Reactions of α, β-Unsaturated Acid Anhydride with β-Aminocrotonamide and Related Compounds
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