Chemical Reactions of Bikaverin

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概要

• 論文の詳細を見る

• Methylation of bikaverin (Ib) with diazomethane afforded monomethylbikaverin (Ic). Reductive acetylation of Ia, b, c with acetic anhydride and sodium acetate in the presence of zinc powder gave rise to benzoxanthene derivatives (IIc, d, e), respectively. Ib was hydrolyzed with aqueous sodium hydroxide to give everninic acid (III) and orcinol (IV). However, hydrolysis of Ic with alcoholic potassium hydroxide gave rise to cyclopentenoxanthene derivative (V). Ozonolysis of Ic gave xanthone derivative (XI).

• 公益社団法人日本薬学会の論文
• 1978-01-25

著者

• 佐藤 雅之

  静岡県立大学薬学部

• 佐藤 雅之

  Pharmaceutical Institute, Tohoku University

• 加藤 鉄三

  東北大学 薬

• 加藤 鉄三

  Pharmaceutical Institute Tohoku University

• 片桐 信弥

  Pharmaceutical Institute, Tohoku University

• 中野 潤

  Kakenyaku-kako Kyoto Research Laboratories

• 片桐 信弥

  Health Sci. Univ. Hokkaido Hokkaido Jpn

• 片桐 信弥

  Pharmaceutical Institute Tohoku University

• 淡路 敏和

  Pharmaceutical Institute, Tohoku University

• 中野 潤

  Pharmaceutical Institute, Tohoku University

• 加藤 鉄三

  Pharmaceutical Institute. Tohoku University

• 淡路 敏和

  Pharmaceutical Institute Tohoku University

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