Reaction of 2,2-Dimethyl-1,3-dioxin-4-one Derivatives with Pyridinium (Isoquinolinium) Methylides and Cyano Compounds
スポンサーリンク
概要
- 論文の詳細を見る
Cycloaddition of acylketenes (2) to 1,2-and 1,3-dipolar compounds was investigated. The thermal reaction of 1,3-dioxin-4-ones (1) with isoquinolinium phenacylide (11) gave the aromatized pyrrolo [2,1-a] isoquinolines (12-15). The reaction of 1 with pyridinium and isoquinolinium cyanomethylides (3-5) afforded the 1,3-oxazinylmethylides (6-8). The intermediate 2 likewise reacted with cyanamides and benzonitriles to give the corresponding 1,3-oxazin-4-one derivatives (19-23).
- 公益社団法人日本薬学会の論文
- 1984-01-25
著者
-
佐藤 雅之
静岡県立大学薬学部
-
佐藤 雅之
Pharmaceutical Institute, Tohoku University
-
鹿沼 徳雄
Pharmaceutical Institute, Tohoku University
-
加藤 鐡三
Pharmaceutical Institute Tohoku University
-
鹿沼 徳雄
Pharmaceutical Institute Tohoku University
関連論文
- A Novel Synthesis of β-Ketothioesters
- A Novel Synthetic Method for Tetronic Acids from 1,3-Dioxin-4-ones via Intra- or Intermolecular Ketene Trapping
- Synthesis of 1,3-Dioxin-4-ones and Their Use in Synthesis. XVIII. : Synthesis of Azetidin-2-ones from 1,3-Dioxin-4-ones via 3-Hydroxycarboxamides
- Studies on Ketene and Its Derivatives. XCV. Reaction of Diketene with Acyl Azides
- Reaction of Diketene-Acetone Adduct with Enamines, Ketene Acetals, Vinyl Ethers, and β-Diketones
- Studies on Ketene and Its Derivatives. CXVIII. Nickel- or Palladium-Catalyzed Reaction of Diketene with Organometallics. Synthesis of 3-Substituted 3-Butenoic Acids
- STUDIES ON KETENE AND ITS DERIVATIVES. CXV. REACTION OF DIKETENE WITH ORGANOMETALLICS IN THE PRESENCE OF THE NICKEL- OR PALLADIUM-PHOSPHINE COMPLEX
- hPIV-1シアリダーゼ阻害活性をもつシアル酸誘導体の合成研究
- 研究開発情報 フルオラス・タグ法による抗シアリダーゼ活性をもつシアル酸誘導体の効率的合成研究
- P2-101 水道水中の変異原物質MXの付加体形成に関する研究(環境変異原)
- ケテン化学の新展開:α-オキソケテンの合成と反応
- Addition of Molecular Fluorine to Azlactones : General Synthetic Method of erythro-β-Fluorinated α-Amino Acids
- Use of 1,3-Dioxin-4-ones and Related Compounds in Synthesis. XLIV. Asymmetric Aldol Reaction of 4-Trimethylsiloxy-6-methylene-1,3-dioxines : Use of Tartaric Acid-Derived (Acyloxy)borane Complex as the Catalyst
- Facile Synthesis of 5α-Fluorocholestan-3-one from 4-Cholesten-3-one via Molecular Fluorine Addition and Reductive Defluorination
- Use of 1,3-Dioxin-4-ones and Related Compounds in Sythesis. XXXVIII. Use of 1,3-Dioxin-4-ones Having a Fluorine or Trifluoromethyl Group at the 5-Position as _π2 Components in [2+2]-Photocycloaddition and Diels-Alder Reactions
- l-MENTHYL (2S)-2-PHENYL-3-(p-ANISYL)-(5Z)-BENZYLIDENE-4,6-DIOXO-1,3-OXAZINE-2-CARBOXYLATE : A NEW CHIRAL HETERODIENE AND MICHAEL ACCEPTOR
- Synthesis of 1,3-Dioxin-4-ones and Their Use in Synthesis XX. : (6S, 7S, 10R)- and (6R, 7S, 10R)-7-Isopropyl-10-mythyl-4-oxo-1,5-dioxaspiro[5.5]undec-2-enes; Synthesis and Their Use in Enantiomerically Pure Corey Lactone Analogue Synthesis
- Synthesis of 1,3-Dioxin-4-ones and Their Use in Synthesis. XVII. : Chiral Spirocyclic 4-Oxo-1,3-dioxin-5-carboxylates : Asymmetric Synthesis of Carbocyclic C-Nucleoside Precursors
- Synthesis of Nucleosides and Their Related Compounds. XII. : Menthyl 2,4-Dioxo-1,3-oxazine-5-carboxylates : New Dienophiles for the Asymmetric Diels-Alder Reaction Directed towards Synthesis of Carbocyclic C-Nucleosides
- Synthesis of 1,3-Dioxin-4-ones and Their Use in Synthesis.XVI. : 4-Oxo-1,3-dioxin-5-carboxylic Acids and Related Compounds : Versatile Synthetic Intermediates for the Synthesis of 6-Unsubstituted Six-Membered Heterocyclic Compunds
- キラルな1,3-ジオキシン-4-オン類の不斉有機合成への利用
- 1,3-ジオキシン-4-オン類の合成と有機合成への応用 : 最近の進歩
- A NEW METHOD FOR INTRODUCING THE 2,2-DICHLOROETHYL GROUP AT THE 3 POSITION OP THE 2-QUINOLONE SYSTEM, AND THE SYNTHESIS OF DICTAMNINE(Communication to the Editor)
- Cycloadditions in Syntheses. XXXII. Intramolecular Photocycloaddition of 4-(ω-Alkenyloxy)quinolin-2(1H)-one: Synthesis of 2-Substituted Cyclobuta[c]quinolin-3(4H)-ones(Organic,Chemical)
- Chemical Reactions of Bikaverin
- Synthesis of β-Ketocarboxamide Derivatives Using 2,2-Dimethyl-2H, 4H-1,3-dioxin-4-ones
- Reaction of 2,2-Dimethyl-1,3-dioxin-4-ones with Imines, Carbodiimides, and Isocyanates
- Reaction of 2,2,6-Trimethyl-1,3-dioxin-4-one with Imines
- Synthesis of 1,3-Dioxin-4-one Derivatives
- Novel Annelation Method to Pyridine and Isoquinoline by Photochemical Means
- Synthesis of N-Acylacetoacetamide using 2,2,6-Trimethyl-1,3-dioxin-4-one
- Studies on Ketene and Its Derivatives. CV. Photoreaction of Diketene with sec-Alcohols
- Synthesis of Methylpyridine Derivatives. XXXIV. Condensation of Acetoacetamide with Ketones to form Pyridone Derivatives
- Studies on Ketene and Its Derivatives. XCII. Reaction of Diketene with Benzaldehyde, Cinnamaldehyde, and β-Phenylcinnamaldehyde
- Studies on Ketene and Its Derivatives. LXXXVII. Photoreaction of Diketene with 3-Acetoxy-5,5-dimethyl-2-cyclohexenone
- Studies on Ketene and Its Derivatives. LXIX. Reaction of Diketene with Hydrazobenzenes
- Studies on Ketene and Its Derivatives. LXVII. Photoreaction of Benzophenone and Benzaldehyde with Diketene
- ケテンおよびその誘導体の研究(第52報)ジケテンとα(β)-アミノニトリルとの反応
- ケテンおよびその誘導体の研究(第51報))α-アミノ酸アミドとジケテンとの反応
- Studies on Ketene and Its Derivatives. XLI. Reaction of α-Aminoketone with Diketene
- Synthesis of 1,3-Dioxin-4-ones and Their Use in Synthesis. XIII. : Synthesis of 5-Halo-1,3-dioxin-4-ones and Their Conversion to 5-Alkyl Derivatives
- Synthesis of 1,3-Dioxin-4-ones and Their Use in Synthesis. XI. : 2,2-Dimethyl-1,3-dioxin-4-one as a Synthetic Equivalent of Formylketene : Synthesis of Heterocyclic Compounds
- Reaction of 2,2,6-Trimethyl-1,3-dioxin-4-one with Isoquinolinium and Pyridinium Ylides
- 1, 3-ジオキシン-4-オン誘導体の合成とその有機合成への利用
- 光化学的周辺環状反応を用いる生理活性化合物の合成
- Reaction of 2,2-Dimethyl-1,3-dioxin-4-one Derivatives with Pyridinium (Isoquinolinium) Methylides and Cyano Compounds
- Studies on Ketene and Its Derivatives. XXXI. 2-Acetonyloxazolines