メチルピリジン誘導体の合成(第25報) : α-置換-2-pyridineacetonitrile誘導体の合成
スポンサーリンク
概要
- 論文の詳細を見る
Reaction of 2-pyridineacetonitrile (II) with aldehydes in the presence of sodium hydroxide or piperidine in ethanol gives α-alkylidene-2-pyridineacetonitrile (V). II does not react with ketones under the same condition but does react with benzophenone in the presence of sodium amide to give α, α-diphenyl-2-pyridineethanol (IX). II easily transits to α-acyl-2-pyridineacetonitrile (X) by reaction with acid halides. Catalytic reduction, hydrolysis, and Grignard reaction of V are also described.
- 公益社団法人日本薬学会の論文
- 1969-02-25
著者
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加藤 鉄三
東北大学医学部薬学科
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白石 隆幸
東北大学薬学部
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加藤 鉄三
Pharmaceutical Institute. Tohoku University
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白石 隆幸
東北大学医学部薬学科
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熱海 駿雄
東北大学医学部薬学科
関連論文
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