Synthesis of Nucleosides and Related Compounds. XVII. Dialkyl 1,3-Dithiethan- and 1,3-Dithiolan-2-ylidenemalonate S-Oxides : Equivalents to Dialkoxycarbonylketenes

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概要

• 論文の詳細を見る

• Dialkyl 1,3-dithiethan- and 1,3-dithiolan-2-ylidenemalonate S-oxides have been found to serve as new dienophiles for Diels-Alder reaction with cyclopentadiene. Furthermore, since the adducts thus obtained were transformed to dialkyl 3-oxobicyclo[2.2.1]heptane-2,2-dicarboxylates, these dienophiles behaved as dialkoxycarbonylketene equivalents.Synthesis of di-l-methyl [1R and 1S]-1,3-dithiethan-2-ylidenemalonate 1-oxides and their successful use in asymmetric Diels-Alder rections with cyclopentadiene are also described.

• 公益社団法人日本薬学会の論文
• 1990-12-25

著者

• 渡辺 信久

  Pharmaceutical Institute Tohoku University

• 金子 主税

  東北大学

• 金子 主税

  Pharmaceutical Institute Medical Faculty University Of Tokyo

• 片桐 信弥

  Pharmaceutical Institute, Tohoku University

• 伊勢 秀也

  Pharmaceutical Institute Tohoku University

• 片桐 信弥

  Health Sci. Univ. Hokkaido Hokkaido Jpn

• 片桐 信弥

  Pharmaceutical Institute Tohoku University

• Katagiri N

  Pharmaceutical Institute Tohoku University

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