Polycyclic N-Hetero Compounds. VIII. Reactions of Ketones with Trisformylaminomethane

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概要

• 論文の詳細を見る

• Reactions of ketones with trisformylaminomethane were described. Except pyrimidine derivatives reported by Bredereck, et al., few by-products were obtained. Thus methyl ethyl ketone (I) gave 4-ethylpyrimidine (III) and 5-methyl-4-(5-pyrimidinyl) pyrimidine (IV), diethyl ketone (V) gave 4-amino-3,5-dimethylpyridine (VII), cyclohexanone (VIII) gave bis (5,6,7,8-tetrahydro-8-quinazolinylidenemethyl) amine (X). 4-Methyl-5-phenylpyrimidine (XII) and 8-phenyl-5,6,7,8-tetrahydroquinazoline (XIV) were obtained from phenylacetone (XI) and 2-phenylcyclohexanone (XIII) respectively. Dehydrogenation of (XIV) with sulfur afforded 8-phenylquinazoline (XV).

• 公益社団法人日本薬学会の論文
• 1975-09-25

著者

• 大和 正利

  Faculty of Science, Okayama University of Science

• 小山 鷹二

  Faculty of Pharmaceutical Sciences, Medical School, Okayama University

• 大森 晋爾

  Faculty of Pharmaceutical Sciences, Medical School, Okayama University

• 廣田 喬

  Faculty Of Pharmaceutical Sciences Okayama University

• 松本 祥子

  Faculty Of Pharmaceutical Sciences Medical School Okayama University

• 大森 晋爾

  Faculty Of Pharmaceutical Sciences Okayama University

• 大和 正利

  Faculty Of Pharmaceutical Sciences Okayama University

• 佐藤 美子

  Faculty Of Pharmaceutical Sciences Medical School Okayama University

• 馬生 千鶴子

  Faculty of Pharmaceutical Sciences, Medical School, Okayama University

• 渡辺 靖子

  Faculty of Pharmaceutical Sciences, Medical School, Okayama University

• 篠原 百里江

  Faculty of Pharmaceutical Sciences, Medical School, Okayama University

• 渡辺 靖子

  Faculty Of Pharmaceutical Sciences Medical School Okayama University

• 馬生 千鶴子

  Faculty Of Pharmaceutical Sciences Okayma University

• 篠原 百里江

  Faculty Of Pharmaceutical Sciences Medical School Okayama University

• 広田 喬

  岡山大学 薬

• 小山 鷹二

  Faculty Of Pharmaceutical Sciences Okayama University

• 馬生 千鶴子

  Faculty Of Pharmaceutical Sciences Okayama University

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