Condensation of Diethyl Acetonedicarboxylate. IV. Regioselective Reaction of Diethyl Acetonedicarboxylate-magnesium Complex
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概要
- 論文の詳細を見る
The reactivity of diethyl acetonedicarboxylate (DADC)-magnesium complex (1a, b) was examined. The Michael reaction of 1a, b gave the regioselectively monoalkylated derivative (2 or 3) of DADC. Reaction of 1a with nucleophilic reagents, LiAlH_4 or alkylamines, took place at the unchelated ethoxycarbonyl group and gave the single corresponding product (7 or 9) with regioselectivity.
- 公益社団法人日本薬学会の論文
- 1981-10-25
著者
-
大和 正利
Faculty Of Pharmaceutical Sciences Okayama University
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楠 洋一郎
Faculty Of Pharmaceutical Sciences Okayama University
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