Reaction of 1,2,3,4-Tetrahydroquinazolin-4-ones with Acid Anhydride. II
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概要
- 論文の詳細を見る
The reaction of 1,2,3,4-tetrahydroquinazoline-2-spirocyclohexan-4-one (1b) with acetic anhydride and pyridine gave 1-(1-cyclohexenyl)-2-methyl-1,4-dihydroquinazolin-4-one (3b). Compound 3b gave 3-acetyl-1-(1-cyclohexenyl)-2-methyl-1,2,3,4-tetrahydroquinazolin-4-one (8b) upon reduction with NaBH_4 followed by acetylation with acetic anhydride. The position of the acetyl group of 8b was determined by comparison of its NMR spectrum with those of related compounds (9,10,11,12,and 13).
- 社団法人日本薬学会の論文
- 1981-10-25
著者
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竹内 靖雄
岡山大学薬学部
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竹内 靖雄
Faculty of Pharmaceutical Sciences, Okayama University
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大和 正利
Faculty of Science, Okayama University of Science
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堀内 次郎
Faculty of Pharmaceutical Sciences, Okayama University
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大和 正利
Faculty Of Pharmaceutical Sciences Okayama University
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竹内 靖夫
Faculty Of Pharmaceutical Sciences Okayama University:cancer Chemotherapy Center
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堀内 次郎
Central Research Institute Mect Corporation
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