Benzylcarbonyl化合物とFormamideとの反応(第5報) : α-Acyl-3,4-dimethoxyphenylacetonitrileとの反応
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概要
- 論文の詳細を見る
On heating α-acyl-3,4-dimethoxyphenylacetonitriles (I) with H_2NCHO and POCl_3,pyrimidines (III) were obtained, but isoquinolines could not isolated : the α-formyl derivative (Ia) gave 4-amino-5-(3,4-dimethoxyphenyl) pyrimidine (IIIa), the α-acetyl derivative (Ib) gave 4-amino-5-(3,4-dimethoxyphenyl)-6-methylpyrimidine (IIIb), and the α-benzoyl derivative (Ic) gave 4-amino-5-(3,4-dimethoxyphenyl)-6-phenylpyrimidine (IIIc). 3,4-Dimethoxyphenylacetonitrile (II) gave IIIa under the same reaction conditions.
- 公益社団法人日本薬学会の論文
- 1970-01-25
著者
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廣田 喬
Faculty Of Pharmaceutical Sciences Okayama University
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大和 正利
Faculty Of Pharmaceutical Sciences Okayama University
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大和 正利
第一薬科大学
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廣田 喬
熊本大学薬学部
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