Polycyclic N-Hetero Compounds. XXIII. : Synthesis and Antidepressive Activity of 4-Substituted 5,6-Dihydrobenzo[h]quinazolines
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概要
- 論文の詳細を見る
4-Alkylamino-5,6-dihydrobenzo[h]quinazolines (IIIa-k) were synthesized by the reaction of 4-chloro-5,6-dihydrobenzo[h]quinazoline (IIc) with primary alkylamines. Screening of 4-amino-(IIa), 4-hydroxy-(IIb), and 4-(2-hydroxyethylamino)-5,6-dihydrobenzo[h]quinazoline (IId), as well as IIc and IIIa-k, for antireserpine action indicated that IId, IIIa, and IIIh exhibited effective antidepressant activity.
- 公益社団法人日本薬学会の論文
- 1986-07-25
著者
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廣田 喬
Faculty Of Pharmaceutical Sciences Okayama University
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佐々木 健一
Faculty of Agriculture, Tokyo University of Agriculture and Technology
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灘波 哲人
Faculty Of Pharmaceutical Sciences Okayama University
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川西 慶子
Faculty of Pharmaceutical Sciences, Okayama University
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川西 慶子
Faculty Of Pharmaceutical Sciences Okayama University
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佐々木 健一
Faculty Of Pharmaceutical Sciences Okayama University
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廣田 喬
Faculty of Pharmaceutical Sciences, Okayama University
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