Benzylcarbonyl化合物とFormamideとの反応(第10報)α-Acyl-α-naphthylacetonitrileとの反応
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概要
- 論文の詳細を見る
α-Acyl-α-naphthylacetonitriles were heated with HCONH_2 and POCl_3,and the following results were obtained. 1) In the case of α-acyl-α-(1-naphthyl) acetonitriles, formyl derivative (IIa) gave 4-amino-5-(1-naphthyl) pyrimidine (IIIa), acetyl derivative (IIb) gave 4-amino-6-methy1-5-(1-naphthyl) pyrimidine (IIIb), and benzoyl derivative (IIc) gave IIIa and benzamide (IV). 2) In the case of α-acyl-α-(2-naphtyl) acetonitrilei, formyl derivative (VIa) gave 4-amino-5-(2-naphthyl) pyrimidine(VII), acetyl derivative (VIb) gave 6-methyl-5-(2-naphthyl)-4-pyrimidone.(VIII), and benroyl derivative (VIc) gave VII and IV.
- 公益社団法人日本薬学会の論文
- 1973-11-25
著者
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廣田 喬
Faculty Of Pharmaceutical Sciences Okayama University
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小山 鷹二
岡山大学医学部附属病院薬剤部
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大和 正利
Faculty Of Pharmaceutical Sciences Okayama University
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廣田 喬
岡山大学医学部薬学科
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大和 正利
岡山大学医学部薬学科
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構木 信也
吉富製薬株式会社
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小山 鷹二
岡山大学医学部付属病院薬剤部
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