Polycyclic N-Hetero Compounds. XIV. Reactions of Methylpyridines with Formamide

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概要

• 論文の詳細を見る

• Reactions of pyridines and condensed pyridines having active methyl group with formamide were described. 2- or 4-methylpyridine (I, IV) gave 5-(2- or 4-pyridyl)-pyrimidine (II, V). 2- or 4-methylquinoline (VI, XI) gave 2- or 4-(5-pyrimidinyl)-quinoline (VII, XII) and 1-formyl-2-or 4-methyl-1,2,3,4-tetrahydroquinoline (IX, XIII). 3,5-Di (2-quinolyl) pyridine (VIII) and 2-(2-pyrazinyl) quinoline (X) were obtained from VI except for VII and IX. 3-Methylisoquinoline (XIV) gave 2-formyl-3-methyl-1,2,3,4-tetrahydroisoquinoline (XV) and quinoline (XVI) gave 1,2,3,4-tetrahydroquinoline (XVIII) and its N-formyl derivative (XVII). Purine (III) was confirmed on thin-layer chromatography in these reactions.

• 公益社団法人日本薬学会の論文
• 1977-08-25

著者

• 大和 正利

  Faculty of Science, Okayama University of Science

• 小山 鷹二

  Faculty of Pharmaceutical Sciences, Medical School, Okayama University

• 大森 晋爾

  Faculty of Pharmaceutical Sciences, Medical School, Okayama University

• 廣田 喬

  Faculty Of Pharmaceutical Sciences Okayama University

• 大森 晋爾

  Faculty Of Pharmaceutical Sciences Okayama University

• 大和 正利

  Faculty Of Pharmaceutical Sciences Okayama University

• 馬生 千鶴子

  Faculty of Pharmaceutical Sciences, Medical School, Okayama University

• 難波 哲人

  Faculty of Pharmaceutical Sciences, Okayama University

• 難波 哲人

  Faculty Of Pharmaceutical Sciences Okayama University

• 広田 喬

  岡山大学 薬

• 小山 鷹二

  Faculty Of Pharmaceutical Sciences Okayama University

• 馬生 千鶴子

  Faculty Of Pharmaceutical Sciences Okayama University

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