Reaction of Anthranilamides with Levulinic Acids. Synthesis of 2,3,3a, 4-Tetrahydropyrrolo [2,1-b] quinazoline-1,9-diones

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概要

• 論文の詳細を見る

• The reaction of 2-(methylamino) benzamide with levulinic acid gave 3a, 4-dimethyl-2,3,3a, 4-tetrahydropyrrolo [2,1-b] quinazoline-1,9-dione (2). 3a-Methyl-2,3,3a, 4-tetrahydropyrrolo [2,1-b] quinazoline-1,9-dione (6) was prepared by the method shown in Chart 3. The compounds 2 and 6 were different from authentic samples A and B prepared by the method reported by previous workers. The real structures of A and B were found to be 3a-methyl-2,3,3a, 4-tetrahydropyrrolo [1,2-a] quinazoline-1,5-dione (9) and 3-(2,3-dimethyl-4-oxo-1,2,3,4-tetrahydro-2-quinazolinyl) propionic acid (10), respectively.

• 社団法人日本薬学会の論文
• 1982-03-25

著者

• 竹内 靖雄

  岡山大学薬学部

• 竹内 靖雄

  Faculty of Pharmaceutical Sciences, Okayama University

• 大和 正利

  Faculty of Science, Okayama University of Science

• 大和 正利

  Faculty Of Pharmaceutical Sciences Okayama University

• 竹内 靖夫

  Faculty Of Pharmaceutical Sciences Okayama University:cancer Chemotherapy Center

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