Asymmetric Synthesis of 1-Benzyltetrahydroisoquinolines Using Chiral Oxazolo[2,3-α]tetrahydro-isoquinolines

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概要

• 論文の詳細を見る

• A novel synthetic route to enantiomerically pure 1-benzyltetrahydroisoquinolines (1) was developed via the reaction of oxazolo[2,3-a]tetrahydroisoquinoline (5) with benzyltriisopropoxytitanium compounds (10). This method was applied to the synthesis of (S)-trimetoquinol (1c; a bronchodilator).

• 社団法人日本薬学会の論文
• 1991-05-25

著者

• 竹内 靖雄

  岡山大学薬学部

• 竹内 靖雄

  Faculty of Pharmaceutical Sciences, Okayama University

• 橋垣 国子

  Faculty of Pharmaceutical Sciences, Okayama University

• 大和 正利

  Faculty of Science, Okayama University of Science

• QAIS Nazumul

  Faculty of Pharmaceutical Sciences, Okayama University

• 管 慶三

  Faculty of Pharmaceutical Sciences, Okayama University

• QAIS Nazmul

  Faculty of Pharmaceutical Sciences, Okayama University

• 大和 正利

  Faculty Of Pharmaceutical Sciences Okayama University

• 大和 正利

  Faculty Of Science Okayama University Of Science

• 竹内 靖夫

  Faculty Of Pharmaceutical Sciences Okayama University:cancer Chemotherapy Center

• Qais Nazumul

  Faculty Of Pharmaceutical Sciences Okayama University

• 橋垣 国子

  Faculty Of Pharmaceutical Sciences Okayama University

• 橋垣 國子

  Faculty Of Pharmaceutical Sciences Okayama University

• 管 慶三

  Faculty Of Pharmaceutical Sciences Okayama University

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• アルドールおよび関連反応におけるChiralなアルデヒドのジアステレオ面選択性

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