Synthesis and Antiulcer Activity of (Isochroman-1-yl)alkylamines. I

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概要

• 論文の詳細を見る

• N-benzyl-2-(isochroman-1-yl)-1-methylethylamine (6f), prepared by the reaction of 1-ethoxy-isochroman (4) and acetone followed by reductive amination, was found to possess inhibitory activity against aspirin-induced ulcer but did not exhibit gastric antisecretory activity. Structural modification of 6f was undertaken and the structure-activity relationships of the derivatives are discussed.

• 公益社団法人日本薬学会の論文
• 1988-05-25

著者

• 橋垣 国子

  Faculty of Pharmaceutical Sciences, Okayama University

• 大和 正利

  Faculty of Science, Okayama University of Science

• 大和 正利

  Faculty Of Pharmaceutical Sciences Okayama University

• 大和 正利

  Faculty Of Science Okayama University Of Science

• 橋垣 国子

  Faculty Of Pharmaceutical Sciences Okayama University

• 人見 進

  Faculty of Pharmaceutical Sciences, Okayama University

• 石川 維孝

  Faculty of Pharmaceutical Sciences, Okayama University

• 苔口 輝美

  Faculty of Pharmaceutical Sciences, Okayama University

• 橋垣 國子

  Faculty Of Pharmaceutical Sciences Okayama University

• 苔口 輝美

  Faculty Of Pharmaceutical Sciences Okayama University

• 石川 維孝

  Faculty Of Pharmaceutical Sciences Okayama University

• 人見 進

  Faculty Of Pharmaceutical Sciences Okayama University

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• アルドールおよび関連反応におけるChiralなアルデヒドのジアステレオ面選択性

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