A New Method for the Preparation of 2-(Alkylamino) benzoxazoles and 2-(Alkylimino) benzoxazolines
スポンサーリンク
概要
- 論文の詳細を見る
New syntheses of 2-(alkylamino) benzoxazoles (III) and 3-alkyl-2-(alkylimino) benzoxazolines (IV) were developed. Various compounds III were obtained by the reactions of 2-(methylthio) benzoxazole with amines. In the alkylation of 2-(monoalkylamino) benzoxazoles, the use of a base as a catalyst was found to be important for the selective preparation of 2-(N, N-dialkylamino) benzoxazoles ; in the absence of base, IV was obtained, On the other hand, alkylation of N, N'-dialkyl-N-(2-hydroxyphenyl) thioureas resulted in the development of another method for the preparation of IV.
- 社団法人日本薬学会の論文
- 1984-08-25
著者
-
竹内 靖雄
岡山大学薬学部
-
竹内 靖雄
Faculty of Pharmaceutical Sciences, Okayama University
-
橋垣 国子
Faculty of Pharmaceutical Sciences, Okayama University
-
服部 京子
Faculty of Pharmaceutical Sciences, Okayama University
-
服部 京子
Faculty Of Pharmaceutical Sciences Okayama University
-
竹内 靖夫
Faculty Of Pharmaceutical Sciences Okayama University:cancer Chemotherapy Center
-
橋垣 国子
Faculty Of Pharmaceutical Sciences Okayama University
-
橋垣 國子
Faculty Of Pharmaceutical Sciences Okayama University
関連論文
- 抗マラリア化合物, Febrifugine の構造と合成
- Alkoxycarbonylmethylation of(3R, 10bS)-3-Phenyl-2,3,5,6-tetrahydro-10bH-oxazolo[2,3-a]isoquinoline
- Synthesis and Antitumor Activity of Fused Quinoline Derivatives. III. Novel N-Glycosylamino-indolo[3,2-b]quinolines
- Synthesis and Antitumor Activity of Fused Quinoline Derivatives. II. Novel 4- and 7-Hydroxyindolo-[3,2-b]quinolines
- Asymmetric syntheses of 1-Alkyltetrahydro-β-carbolines and a 9-Thio Analogue
- SYNTHESIS AND ANTITUMOR ACTIVITY OF 7-(N-GLYCOSYLAMINO)-INDOLO[3,2-b]QUINOLINES
- Asymmetric Synthesis of 1-Benzyltetrahydroisoquinolines Using Chiral Oxazolo[2,3-α]tetrahydro-isoquinolines
- Synthesis and Antitumor Activity of Fused Quinoline Derivatives
- The Wittig Reaction of Benzofuran-2,3-diones
- Syntheses and Antifungal Activities of dl-Griseofulvin and Its Congeners. I
- A Practical Synthetic Method for β-Ketoesters from Ketones
- One-Flask Synthesis of Sulfides from Alcohols and Alkyl Halides Using Benzoxazoline-2-thione
- A New Method for the Preparation of 2-(Alkylamino) benzoxazoles and 2-(Alkylimino) benzoxazolines
- A New Method for the Preparation of 2-Alkoxybenzoxazoles
- Synthesis of 3-Substituted Benzoxazoline-2-thiones
- Reaction of Benzoxazoline-2-thiones with Alkyl Halides
- Reaction of Anthranilamides with Levulinic Acids. Synthesis of 2,3,3a, 4-Tetrahydropyrrolo [2,1-b] quinazoline-1,9-diones
- Reaction of 1,2,3,4-Tetrahydroquinazolin-4-ones with Acid Anhydride. IV
- Reaction of 1,2,3,4-Tetrahydroquinazolin-4-ones with Acid Anhydride. III
- Reaction of 1,2,3,4-Tetrahydroquinazolin-4-ones with Acid Anhydride. II
- THE SYNTHESIS AND ANTITUMOR ACTIVITIES OF TROPOLONE AND 8-HYDROXYQUINOLINE DERIVATIVES
- Condensation of Diethyl Acetonedicarboxylate. II
- Condensation of Diethyl Acetonedicarboxylate. I
- Chemical Structure and Sweet Taste of Isocoumarin and Related Compounds. VI
- 抗腫瘍性トロポロン誘導体処理によるマウス乳癌細胞FM3Aにおけるデオキシヌクオシド三リン酸の不均衡とDNA二重鎖開裂(発表論文抄録(1991年))
- Synthesis and Structure-Activity Relationship of Spiro [isochroman-piperidine] Analogs for Inhibition of Histamine Release. IV.
- Synthesis and Structure-Activity Relationship of Spiro [isochroman-piperidine] Analogs for Inhibition of Histamine Release. III
- Diphenylethane系化合物の立体構造
- Chemical Structure and Sweet Taste of Isocoumarin and Related Compounds. IX
- Chemical Structure and Sweet Taste of Isocoumarin and Related Compounds. VII
- Isocoumarin誘導体および関連化合物の呈する甘味と化学構造について(第5報)
- Chemical Structure and Sweet Taste of Isocoumarins and Related Compounds
- Isocoumarin誘導体および関連化合物の呈する甘味と化学構造について(第4報)
- Chemical Structure and Sweet Taste of Isocoumarins and Related Compounds. X. Syntheses of Sweet 5-Hydroxyflavanones and Related Dihydrochalcones
- Chemical Structure and Sweet Taste of Isocoumarins and Related Compounds Synthesis of 5-Hydroxyflavanones and Related Dihydrochalcones
- Chemical Structure and Sweet Taste of Isocoumarin and Related Compounds. VIII
- Synthesis and Structure-Activity Relationship of Spiro [isochroman-piperidine] Analogs for Inhibition of Histamine Release. II
- Synthesis and Antiulcer Activity of (Isochroman-1-yl)alkylamines. II
- Synthesis and Antiulcer Activity of (Isochroman-1-yl)alkylamines. I
- ANTITUMOR ACTIVITY OF ISOCHROMANYLTROPOLONES
- Synthesis and Biological Activity of Spiro [isocoumarin-piperidines] and Reltaed Compounds. I
- Reaction of Spiro[piperidine-4,2'-(1', 2', 3', 4'-tetrahydroquinazolin)]-4'-ones with Acid Anhydrides
- 生理活性を有するIsocoumarin誘導体の合成(第1報) : 3,4-Dihydroisocoumarin類の甘味と化学構造について
- Synthesis of dl-Agrimonolide (Constituent of Rhizome of Agrimonia pilosa LEDEB)
- 生理活性を有するIsocoumarin誘導体の合成(第3報)3,4-Dihydroiso-coumarin類の甘味と化学構造について
- 生理活性を有するIsocoumarin誘導体の合成(第2報)3,4-Dihydroisocoumarin類の甘味と化学構造について