Synthesis and Structure-Activity Relationship of Spiro [isochroman-piperidine] Analogs for Inhibition of Histamine Release. III

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概要

• 論文の詳細を見る

• Several 1-alkyl-4-piperidylidene analogs were synthesized and tested for inhibitory activity on the compound 48/80-induced release of histamine from mast cells. 4-(4-Isochromanylidene) (12b) and 4-(diphenylmethylene) (14) derivatives of 1-benzylpiperidine were much more active than the lead compounds, 1-benzylspiro [isochroman-piperidines] (1b and 2b).

• 公益社団法人日本薬学会の論文
• 1983-02-25

著者

• 平松 研

  Faculty Of Pharmaceutical Sciences Okayama University

• 橋垣 国子

  Faculty of Pharmaceutical Sciences, Okayama University

• 大和 正利

  Faculty of Science, Okayama University of Science

• 田坂 賢二

  Faculty of Pharmaceutical Sciences, Okayama University

• 田坂 賢二

  Faculty Of Pharmaceutical Sciences Okayama University

• 大和 正利

  Faculty Of Pharmaceutical Sciences Okayama University

• 橋垣 国子

  Faculty Of Pharmaceutical Sciences Okayama University

• 橋垣 國子

  Faculty Of Pharmaceutical Sciences Okayama University

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