Absolute Stereostructures of Olibanumols A, B, C, H, I, and J from Olibanum, Gum-Resin of Boswellia carterii, and Inhibitors of Nitric Oxide Production in Lipopolysaccharide-Activated Mouse Peritoneal Macrophages

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概要

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• Three new monoterpenes, olibanumols A (1), B (2), and C (3), and three new triterpenes, olibanumols H (4), I (5), and J (6), were isolated from olibanum, the exuded gum-resin from Boswellia carterii BIRDW. Their structures including the absolute configuration were determined by chemical and physicochemical evidence. Among the constituents, olibanumols A (1), H (4), and I (5), and isofouquierol (12) exhibited nitric oxide production inhibitory activity in lipopolysaccharide-activated mouse peritoneal macrophages.

• 社団法人 日本薬学会の論文

著者

• MATSUDA Hisashi

  Kyoto Pharmaceutical University

• YOSHIKAWA Masayuki

  Kyoto Pharmaceutical University

• Morikawa Toshio

  Kyoto Pharmaceutical University

• 森川 敏生

  Pharmaceutical Res. And Technol. Inst. Kinki Univ.

• 吉川 雅之

  Kyoto Pharmaceutical Univ.

• Oominami Hideo

  Kyoto Pharmaceutical University

• 山崎 幹夫

  千葉大学薬学部

• 山崎 幹夫

  千葉大学薬学部医薬品素材学講座

• Yamazaki Masatoshi

  Faculty Of Pharmaceutical Sciences Teikyo University Sagamiko

• Yamazaki M

  School Of Pharmaceutical Sciences Kinki University

• Morikawa T

  Research Institute Fuji Chemical Industries Ltd.

• MATSUDA HISASHI

  Kyoto College of Pharmacy

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