Medicinal Flowers. XII. New Spirostane-Type Steroid Saponins with Antidiabetogenic Activity from Borassus flabellifer
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概要
- 論文の詳細を見る
The methanolic extract from the male flowers of Borassus flabellifer was found to inhibit the increase of serum glucose levels in sucrose-loaded rats at a dose of 250mg/kg, p.o. From the methanolic extract, six new spirostane-type steroid saponins, borassosides A-F (1-6), were isolated together with 23 known constituents. The structures of borassosides (1-6) were elucidated on the basis of chemical and physicochemical evidences. In addition, the principal steroid saponin, dioscin (13), inhibited the increase of serum glucose levels in sucrose-loaded rats at a dose of 50mg/kg,p.o.
- 公益社団法人日本薬学会の論文
- 2007-02-01
著者
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NAKAMURA Seikou
Kyoto Pharmaceutical University
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MATSUDA Hisashi
Kyoto Pharmaceutical University
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YOSHIKAWA Masayuki
Kyoto Pharmaceutical University
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Morikawa Toshio
Kyoto Pharmaceutical University
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森川 敏生
Pharmaceutical Res. And Technol. Inst. Kinki Univ.
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吉川 雅之
Kyoto Pharmaceutical Univ.
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ASAO Yasunobu
Kyoto Pharmaceutical University
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山崎 幹夫
千葉大学薬学部
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松田 秀秋
近畿大学 薬学部
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Miyashita Hiroyuki
三重大学 医学部内科学第2
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Mitani Hidetsugu
三重大学 第2内科
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Xu Fengming
Kyoto Pharmaceutical University
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Yamazaki M
School Of Pharmaceutical Sciences Kinki University
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前田 初男
大阪大学大学院薬学研究科分子薬科学専攻
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PONGPIRIYADACHA Yutana
Kyoto Pharmaceutical University
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Asao Y
Kyoto Pharmaceutical University
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KUMAHARA Akira
Kyoto Pharmaceutical University
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松田 久司
Kyoto Pharmaceutical Univ.
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Nakamura Seikou
Department Of Applied Biology Kyoto Institute Of Technology
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Pongpiriyadacha Yutana
Fac. Of Sci. And Technol. Rajamangala Univ. Of Technol. Srivijaya
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MATSUDA HISASHI
Kyoto College of Pharmacy
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