Medicinal Flowers. XXVI. Structures of Acylated Oleanane-Type Triterpene Oligoglycosides, Yuchasaponins A, B, C, and D, from the Flower Buds of Camellia oleifera : Gastroprotective, Aldose Reductase Inhibitory, and Radical Scavenging Effects
スポンサーリンク
概要
- 論文の詳細を見る
The methanolic extract and its 1-butanol-soluble fraction from the flower buds of Camellia oleifera ABEL were found to exhibit inhibitory effects on ethanol- and indomethacin-induced gastric mucosal lesions in rats. The ethyl acetate- and 1-butanol-soluble fractions also showed inhibitory effects on rat lens aldose reductase and scavenging effects on 1,1-diphenylpicryl-2-hydrazyl radical and superoxide. From the 1-butanol-soluble fraction, four new acylated oleanane-type triterpene oligoglycosides, yuchasaponins A, B, C, and D, were isolated and their structures were elucidated on the basis of chemical and physicochemical evidence. On the other hand, quercetin 3-O-α-L-rhamnopyranoside and kaempferol 3-O-α-L-rhamnopyranoside were isolated from the ethyl acetate- and 1-butanol-soluble fractions as the principal constituents, and their gastroprotective effects were examined.
- 2009-03-01
著者
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SUGIMOTO Sachiko
Kyoto Pharmaceutical University
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NAKAMURA Seikou
Kyoto Pharmaceutical University
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MATSUDA Hisashi
Kyoto Pharmaceutical University
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YOSHIKAWA Masayuki
Kyoto Pharmaceutical University
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吉川 雅之
Kyoto Pharmaceutical Univ.
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山崎 幹夫
千葉大学薬学部
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松田 秀秋
近畿大学 薬学部
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山崎 幹夫
千葉大学薬学部医薬品素材学講座
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CHI Guihua
Kyoto Pharmaceutical University
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KATO Yasuyo
Kyoto Pharmaceutical University
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Miwa H
Second Department Of Internal Medicine Mie University School Of Medicine
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Miyashita Hiroyuki
三重大学 医学部内科学第2
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Mitani H
Second Department Of Internal Medicine Mie University School Of Medicine
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Mitani Hidetsugu
Division Of Hematology And Oncology Suzuka General Hospital
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Mitani Hidetsugu
三重大学 第2内科
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Yoshikawa M
Program In Tissue Engineering Department Of Parasitology Nara Medical University
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YASHIRO Kenichi
Kyoto Pharmaceutical University
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Miwa Hiroshi
三重大学 第2内科
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Yamazaki Masatoshi
Faculty Of Pharmaceutical Sciences Teikyo University Sagamiko
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山田 美紀子
Faculty Of Pharmaceutical Sciences Chiba University
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Matsuda Hajime
Nihon Shokuhin Kako Co. Ltd.
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Yamazaki M
School Of Pharmaceutical Sciences Kinki University
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Matsuda Hideaki
Laboratory Of Natural Drug Resources Faculty Of Pharmacy Kinki University
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前田 初男
大阪大学大学院薬学研究科分子薬科学専攻
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前田 初男
大阪大学大学院薬学研究科
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Maeda H
Faculty Of Pharmaceutical Sciences Osaka University
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Maeda Hatsuo
Faculty Of Pharmaceutical Sciences Osaka University
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Maeda Haruka
The Institute Of Physical And Chemical Research(riken)
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松田 久司
Kyoto Pharmaceutical Univ.
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Nakamura Seikou
Department Of Applied Biology Kyoto Institute Of Technology
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Nakamura Seikou
Department of Applied Biology, Kyoto Institute of Technology
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MATSUDA HISASHI
Kyoto College of Pharmacy
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