Medicinal Flowers. XVI. New Dammarane-Type Triterpene Tetraglycosides and Gastroprotective Principles from Flower Buds of Panax ginseng
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概要
- 論文の詳細を見る
The oligoglycoside fraction from the flower buds of Panax ginseng C. A. MEYER (Araliaceae) was found to show protective effects on ethanol-induced gastric mucosal lesions in rats. From the oligoglycoside fraction, new dammarane-type triterpene tetraglycosides, floralginsenosides M, N, O, and P, were isolated together with the major oligoglycosides ginsenoside Rd and Re. The structures of the new floralginsenosides were elucidated on the basis of chemical and physicochemical evidence. Ginsenoside Rd (protopanaxadiol 3,20-O-bisdesmoside) exhibited inhibitory effects on ethanol- and indomethacin-induced gastric mucosal lesions in rats.
- 公益社団法人日本薬学会の論文
- 2007-07-01
著者
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SUGIMOTO Sachiko
Kyoto Pharmaceutical University
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NAKAMURA Seikou
Kyoto Pharmaceutical University
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MATSUDA Hisashi
Kyoto Pharmaceutical University
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YOSHIKAWA Masayuki
Kyoto Pharmaceutical University
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吉川 雅之
Kyoto Pharmaceutical Univ.
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山崎 幹夫
千葉大学薬学部
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松田 秀秋
近畿大学 薬学部
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Miyashita Hiroyuki
三重大学 医学部内科学第2
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Mitani Hidetsugu
三重大学 第2内科
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Yamazaki M
School Of Pharmaceutical Sciences Kinki University
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前田 初男
大阪大学大学院薬学研究科分子薬科学専攻
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SAKUMAE Hayaka
Kyoto Pharmaceutical University
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松田 久司
Kyoto Pharmaceutical Univ.
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Nakamura Seikou
Department Of Applied Biology Kyoto Institute Of Technology
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MATSUDA HISASHI
Kyoto College of Pharmacy
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