Bioactive Saponins and Glycosides. II. Senegae Radix. (2) : Chemical Structures, Hypoglycemic Activity, and Ethanol Absorption-Inhibitory Effect of E-Senegasaponin c, Z-Senegasaponin c, and Z-Senegins II, III, and IV
スポンサーリンク
概要
- 論文の詳細を見る
Following the characterization of E-senegasaponins a and b and Z-senegasaponins a and b, new bioactive saponins named E-senegasapinin c and Z-senegasapinin c were isolated from Senegae Radix, the root of Polygala senega L. var. latifolia TORREY et GRAY., together with Z-senegins II, III, and IV. The chemical structures of E and Z-senegasaponins c and Z-senegins II, III, and IV were elucidated on the basis of chemical and physicochemical evidence, and the geometrical isomerc structures of the 4''-methoxycinnamoyl and 3'', 4''-dimethoxycinnamoyl groups in these saponins were found to show tautomer-like behavior under irradiation with fluorescent lamps.E and Z-Senegasaponins c and E and Z-senegins II, III, and IV were found to exhibit hypoglycemic activity in the oral D-glucose tolerance test. (E) and (Z)-Senegins II also showed an inhibitory effect on alcohol absorption in rats.
- 公益社団法人日本薬学会の論文
- 1996-07-15
著者
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MATSUDA Hisashi
Kyoto Pharmaceutical University
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YOSHIKAWA Masayuki
Kyoto Pharmaceutical University
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MURAKAMI Toshiyuki
Kyoto Pharmaceutical University
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KADOYA Masashi
Kyoto Pharmaceutical University
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MURAKAMI Nobutoshi
Kyoto Pharmaceutical University
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上野 高裕
Kyoto Pharmaceutical University
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角谷 真
京都薬科大学
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YAMAHARA Johji
Kyoto Pharmaceutical University
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UENO Takahiro
Kyoto Pharmaceutical University
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Kubo M
School Of Pharmaceutical Sciences Kinki University
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Kubo Michinori
近畿大学 薬学部
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植田 知彦
京都薬科大学
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UEMURA Toshiaki
Kyoto Pharmaceutical University
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村上 啓寿
阪大院薬:presto
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Yamahara J
Kyoto Pharmaceutical University
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Uemura Toshiaki
Department Of Information Electronics Graduate School Of Engineering Nagoya University
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Ueno Takahiro
Department Of Respiratory Diseases Institute Of Clinical Medicine University Of Tsukuba
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Ueno T
Kyoto Pharmaceutical University
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Ueno Takahiro
Graduate Course Of Mechanical Engineering Mie University
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Kubo M
Faculty Of Pharmaceutical Sciences Tokushima Bunri University
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YAMAHARA JOHJI
Kyoto College of Pharmacy
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MATSUDA HISASHI
Kyoto College of Pharmacy
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Murakami Toshiyuki
Kyoto Institute of Technology
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