Pharmacological Properties of Traditional Medicines (XXI) : Analysis of Plasma, Urine and Bile of Rats after Oral Administration of Water Extract of Mori Cortex
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概要
- 論文の詳細を見る
In search of the bioactive substances in Mori Cortex (JPXII), a Mori Cortex extract (MCE) was orally administered to rats, and the characteristic constituents in plasma, urine and bile were analyzed by three dimensional high-performance liquid chromatography (3D-HPLC). Mulberroside A and cis-mulberroside A were detected in plasma, oxyresveratrol, oxyresveratrol 2,3'-O-β-D-diglucuronide and oxyresveratrol 2-0-β-D-glucuronide-3'-O-sulfate in urine and mulberroside A, oxyresveratrol, oxyresveratrol 2,3'-O-β-D-diglucuronide and oxyresveratrol 2-O-β-D-glucuronide-3'-O-sulfate in bile. The origin of these metabolites was considered to be mainly derived from mulberroside A in Mori Cortex.
- 日本生薬学会の論文
- 1996-04-20
著者
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Qiu F
Shenyang Pharmaceutical Univ. Shenyang Chn
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Qiu Feng
Department Of Kampo Medicinal Science Hokkaido College Of Pharmacy
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Qiu Feng
Laboratory Of Drug Metabolism And Pharmacokinetics Shenyang Pharmaceutical University
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Saito K
Department Of Kampo Medicinal Science Hokkaido College Of Pharmacy
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Kano Y
Department Of Traditional Medicinal Science Hokkaido College Of Pharmacy
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Kano Yoshihiro
Department Of Kampo Medicinal Science Hokkaido College Of Pharmacy
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Yao Xinsheng
Shenyang Pharmaceutical University
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SAITO Ken-ichi
Department of Kampo Medicinal Science, Hokkaido College of Pharmacy
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KOMATSU Ken-ichi
Department of Kampo Medicinal Science, Hokkaido College of Pharmacy
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KAWASAKI Kanako
Department of Kampo Medicinal Science, Hokkaido College of Pharmacy
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Komatsu Ken-ichi
Department Of Kampo Medicinal Science Hokkaido College Of Pharmacy
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Kano Yoshihiro
Department Of Gastroenterological Surgery Osaka University Graduate School Of Medicine
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