Four New Andrographolide Metabolites in Human Urine
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概要
- 論文の詳細を見る
Andrographolide is one of principal components of a famous traditional Chinese herbal medicine Andrographis paniculate (BURM) NEES. Four new metabolites of andrographolide were isolated from human urine. All of them were characterized as sulfate and one of them also as a cysteine S-conjugate. The structures were determined to be andrographolide-3-O-sulfate (M-1), isoandrographolide-3-O-sulfate (M-2), 14-deoxyandro-grapholide-3-O-sulfate (M-3), 14-deoxy-12-(cysteine-S-yl)-andrographolide-3-0-sulfate (M-4), respectively, based on chemical evidence and spectroscopic analyses.
- 公益社団法人日本薬学会の論文
- 2004-06-01
著者
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Qiu Feng
Department Of Natural Products Chemistry 81# Shenyang Pharmaceutical University
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Qiu Feng
Department Of Kampo Medicinal Science Hokkaido College Of Pharmacy
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YAO Xinsheng
Department of Natural Products Chemistry, Shenyang Pharmaceutical
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Qiu Feng
Department Of Natural Products Chemistry Shenyang Pharmaceutical University
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CUI Liang
Department of Natural Products Chemistry, Shenyang Pharmaceutical University
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WANG Naili
Department of Natural Products Chemistry, Shenyang Pharmaceutical University
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WANG Naili
Life Science Division, Graduate School at Shenzhen, Tsinghua University
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Cui Liang
Department Of Natural Products Chemistry Shenyang Pharmaceutical University
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Wang Naili
Life Science Division Graduate School At Shenzhen Tsinghua University
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Yao Xinsheng
Department Of Natural Products Chemistry 81# Shenyang Pharmaceutical University
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Yao Xinsheng
Department Of Natural Products Chemistry Shenyang Pharmaceutical University:traditional Chinese Medi
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Qiu Feng
Dep. Of Natural Products Chemistry 81# Shenyang Pharmaceutical Univ.
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