Microbial Production of 2-Deoxyribose 5-Phosphate from Acetaldehyde and Triosephosphate for the Synthesis of 2'-Deoxyribonucleosides(Microbiology & Fermentation Technology)

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概要

• 論文の詳細を見る

• 2-Deoxyribose 5-phosphate was produced from acetaldehyde and dihydroxyacetone phosphate via D-glyceraldehyde 3-phosphate by Klebsiella pneumoniae B-4-4 through deoxyriboaldolase- and triosephosphate isomerase-catalyzing reactions. Under the optimum conditions, 98.7 mM 2-deoxyribose 5-phosphate was produced from 200 mM acetaldehyde and 117 mM dihydroxyacetone phosphate in 2 h with a molar yield of 84%. The 2-deoxyriobse 5-phosphate produced was directly transformed to 2'-deoxyribonucleoside by phosphopentomutase- and nucleoside phosphorylasecatalyzing reactions.

• 社団法人日本農芸化学会の論文
• 2003-04-23

著者

• Shimizu Sakayu

  Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University

• Ogawa Jun

  Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University

• Sakai Takafumi

  Division Of Applied Life Sciences Graduate School Of Agriculture Kyoto University

• Sakai T

  Kyoto Univ. Kyoto Jpn

• Shimizu Sakayu

  Division Of Applied Life Science Graduate School Of Agriculture Kyoto University

• Saito K

  Department Of Kampo Medicinal Science Hokkaido College Of Pharmacy

• Takuwa K

  Suntory Institute For Bioorganic Research

• Mikami Y

  Chiba Univ. Chiba Jpn

• Sakai T

  Kikkoman Corp. Chiba Jpn

• HORINOUCHI Nobuyuki

  Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University

• Ogawa Jun

  Division Of Applied Life Sciences Graduate School Of Agriculture Kyoto University

• KAWANO Takako

  Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University

• SAITO Kyota

  Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University

• MATSUMOTO Seiichiro

  Tokyo Laboratory, Yuki Gosei Kogyo Co., Ltd.

• SASAKI Mie

  Tokyo Laboratory, Yuki Gosei Kogyo Co., Ltd.

• MIKAMI Yoichi

  Tokyo Laboratory, Yuki Gosei Kogyo Co., Ltd.

• 斉藤 謙一

  Department Of Physiology And Anatomy Nihon University College Of Pharmacy

• Sakai Toshio

  Division Of Applied Life Sciences Graduate School Of Agriculture Kyoto University

• Takagi S

  Ehime Prefectural Fisheries Experimental Station

• Sasaki M

  Tokyo Laboratory Yuki Gosei Kogyo Co. Ltd.

• Kawano T

  Dep. Of Biological And Environmental Chemistry Fac. Of Agriculture Tottori Univ.

• Mikami Yoichi

  Tobacco Science Research Laboratory

• Mikami Yoichi

  Central Research Institute The Japan Tobacco 〓 Salt Public Corporation

• Saguchi Ken-ichi

  Laboratory Of Biopharmaceutics School Of Pharmaceutical Sciences Showa University

• Shinozaki Kazuo

  Riken Kanagawa Jpn

• Kawano T

  Department Of Biological And Environmental Chemistry Faculty Of Agriculture Tottori University

• Mikami Y

  Tokyo Laboratory Yuki Gosei Kogyo Co. Ltd.

• Sasaki Kanako

  Riken Kanagawa Jpn

• Kawano Tsuyoshi

  Dep. Of Bioresource Sciences Fac. Of Agriculture Tottori Univ.

• Kawano Tsuyoshi

  Department Of Biological And Environmental Chemistry Tottori University

• Kono Takaharu

  Department Of Agricidtural Chemistry Faculty Of Agriculture The University Of Tokyo

• Horinouchi Nobuyuki

  Division Of Applied Life Sciences Graduate School Of Agriculture Kyoto University

• Sakoda K

  Department Of Analytical Chemistry Faculty Of Pharmaceutical Sciences Hoshi University

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