Inhibitory Effects of Capsaicinoids on Fatty Acid Desaturation in a Rat Liver Cell Line(Food & Nutrition Science)
スポンサーリンク
概要
- 論文の詳細を見る
The inhibitory effects of such vanillylamides as capsaicin and nine capsaicinoids on fatty acid desaturation in liver cells were investigated by using the cultured rat liver cell line, BRL-3A. When capsaicin was added to the medium, it had a relatively strong inhibitory effect on Δ6 desaturation and clear inhibitory effects on Δ5 and C24Δ6 desaturation (Δ6 desaturation of C24-polyunsaturated fatty acids). Capsaicinoids with side carbon chain lengths of C10 : 0 and 12 : 0 expressed the maximum inhibitory effects of the nine capsaicinoids on fatty acid desaturation in the BRL-3A cells. The inhibitory effects of the capsaicinoids were not correlated with their pungency.
- 社団法人日本農芸化学会の論文
- 2001-08-23
著者
-
Shimizu Sakayu
Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University
-
WATANABE Tatsuo
School of Food and Nutritional Sciences, University of Shizuoka
-
Shimizu Sakayu
Division Of Applied Life Science Graduate School Of Agriculture Kyoto University
-
SHIRASAKA Norifumi
Department of Agricultural Chemistry, Faculty of Agriculture, Kyoto University
-
YOSHIZUMI Hajime
Department of Food and Nutrition, Faculty of Agriculture, Kinki University
-
MURAKAMI Tetsuo
Department of Food and Nutrition, Faculty of Agriculture, Kinki University
-
NAKANO Nobuhiro
Department of Food Science and Nutrition, Faculty of Agriculture, Kinki University
-
MASUOKA Kazuki
Department of Food Science and Nutrition, Faculty of Agriculture, Kinki University
-
KOBATA Kenji
School of Food and Nutritional Sciences, University of Shizuoka
-
Shirasaka N
Kinki Univ. Nara Jpn
-
Shirasaka Norifumi
Department Of Food Science And Nutrition Faculty Of Agriculture Kinki University
-
Shirasaka Norifumi
近畿大学 農学部
-
Shirasaka Norifumi
Department Of Agricultural Chemistry Kyoto University
-
Kobata Kenji
School Of Food And Nutritional Sciences University Of Shizuoka
-
Masuoka Kazuki
Department Of Food Science And Nutrition Faculty Of Agriculture Kinki University
-
NAKANO Nobuhiro
Atopy (Allergy) Research Center, Juntendo University School of Medicine
-
Watanabe Tatsuo
School Of Food And Nutritional Sciences Univ. Of Shizuoka
-
Nakano Nobuhiro
Atopy (allergy) Research Center Juntendo University School Of Medicine
-
Nakano Nobuhiro
Department Of Dermatology Atopy Research Center Juntendo University School Of Medicine
-
Yoshizumi Hajime
Department Of Food Science And Nutrition Faculty Of Agriculture Kinki University
-
Yoshizumi Hajime
Institute For Fundamental Research Research Center
-
Yoshizumi Hajime
Kinki University
-
Yoshizumi Hajime
Department Of Food And Nutrition Faculty Of Agriculture Kin-ki University
-
Matsuo Takuya
First Department Of Anatomy Kinki University School Of Medicine
-
Matsuo Takuya
Department Of Food Science And Nutrition Faculty Of Agriculture Kinki University
-
Kobata Kenji
School Of Food And Nutritional Sciences And Coe Program In The 21st Century University Of Shizuoka
-
Watanabe Tatsuo
School Of Food And Nutritional Sciences And Coe Program In The 21st Century University Of Shizuoka
-
MURAKAMI Tetsuo
Department of Food and Nutrition Faculty of Agriculture Kinki University
関連論文
- Acidolysis and Glyceride Synthesis Reactions Using Fatty Acids with Two Pseudomonas Lipases Having Different Substrate Specificities(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
- Cloning, sequencing and expression analysis of a gene encoding alcohol oxidase in Paenibacillus sp. AIU 311(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
- Alkaline pH enhances farnesol production by Saccharomyces cerevisiae(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
- Production and characterization of alcohol oxidase from Penicillium purpurescens AIU 063(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
- Purification and Characterization of a New Aldehyde Oxidase from Pseudomonas sp. AIU 362(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
- Superoxide Dismutases Exhibit Oxidase Activity on Aldehyde Alcohols Similar to Alcohol Oxidase from Paenibacillus sp. AIU 311(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
- Purification and Characterization of a Novel Alcohol Oxidase from Paenibacillus sp. AIU 311(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
- Assessment of the Biological Similarity of Three Capsaicin Analogs (Capsinoids) Found in Non-Pungent Chili Pepper (CH-19 Sweet) Fruits
- Different Specificity of Two Types of Pseudomonas Lipases for C20 Fatty Acids with a Δ5 Unsaturated Double Bond and Their Application for Selective Concentration of Fatty Acids (ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
- Identification of mutation sites on Δ12 desaturase genes from Mortierella alpina 1S-4 mutants(GENETICS, MOLECULAR BIOLOGY, AND GENE ENGINEERING)
- Identification of mutation sites on ω3 desaturase genes from Mortierella alpina 1S-4 mutants(GENETICS, MOLECULAR BIOLOGY, AND GENE ENGINEERING)
- Various Oils and Detergents Enhance the Microbial Production of Farnesol and Related Prenyl Alcohols(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
- Identification of Mutation Sites on Δ6 Desaturase Genes from Mortierella alpina 1S-4 Mutants
- Capsinoids, non-pungent capsaicin analogs, reduce body fat accumulation without weight rebound unlike dietary restriction in mice
- Old Yellow Enzyme from Candida macedoniensis Catalyzes the Stereospecific Reduction of the C=C Bond of Ketoisophorone(Microbiology & Fermentation Technology)
- Isolation and Primary Structural Analysis of Two Conjugated Polyketone Reductases from Candida parapsilosis(Biochemistry & Molecular Biology)
- Moecular Cloning and Overexprssion of the Gene Encoding an NADPH-Dependent Carbonyl Reducatase from Candida magnoliae, Involved in Stereoselective Reduction of Ethyl 4-Chloro-3-oxobutanoate
- Diversity of 4-Chloroacetoacetate Ethyl Ester-Reducing Enzymes in Yeasts and Their Application to Chiral Alcohol Synthesis
- Occurrence of Multiple Ethyl 4-Chloro-3-Oxobutanoate-Reducing Enzymes in Candida magnoliae
- Distribution of Threonine Aldolase Activity with Different Stereospecificities in Aerobic Bacteria
- Purification and Characterization of NADPH-Dependent Carbonyl Reductase, Involved in Stereoselective Reduction of Ethyl 4-Chloro-3-oxobutanoate, from Candida magnoliae
- Escherichia coli Transformant Expressing the Glucose Dehydrogenase Gene from Bacillus megaterium as a Cofactor Regenerator in a Chiral Alcohol Production System
- The characteristics of desaturation of Trichoderma sp. AM076 and formation of 9,12,15-hexadecatrienoic acid (16:3ω1) through Δ15 desaturation of 9,12-hexadecadienoic acid
- Microbial Synthesis of trans Isomer of Eicosapentaenoic Acid (EPA) from the Chemically Synthesized Trans Isomer of Linolenic Acid by a Δ12 Desaturase-defective Mutant of Mortierella alpina 1S-4(Microbiology & Fermentation Technology)
- Inhibitory Effects of Capsaicinoids on Fatty Acid Desaturation in a Rat Liver Cell Line(Food & Nutrition Science)
- C19 Odd-chain Polyunsaturated Fatty Acids (PUFAs) Are Metabolized to C21-PUFAs in a Rat Liver Cell Line, and Curcumin, Gallic Acid, and Their Related Compounds Inhibit Their Desaturation
- Formation of 8, 11, 14-Octadecatrienoic Acid (18:3 n-4) from Naturally Occurring Unique Fatty Acid, 9, 12-Hexadecadienoic Acid (16:2 n-4), in Animal Cell Cultures
- Cloning, Sequence Analysis, and Expression in Escherichia coli of the Gene Encoding Monovalent Cation-activated Levodione Reductase from Corynebacterium aquaticum M-13
- Enzymes Involved in the NADPH Regeneration System Coupled with Asymmetric Reduction of Carbonyl Compounds in Microorganisms
- Novel Enzymatic Production of D-(-)-Pantoyl Lactone through the Stereospecific Reduction of Ketopantoic Acid(Microbiology & Fermentation Industry)
- Capsinoids, Non-Pungent Capsaicin Analogs, Reduce Body Fat Accumulation without Weight Rebound unlike Dietary Restriction in Mice
- Identification of Mutation Sites on Δ5 Desaturase Genes from Mortierella alpina 1S-4 Mutants(Microbial Physiology and Biotechnology)
- Characterization of the Second Form of NADH-Cytochrome b_5 Reductase Gene from Arachidonic Acid-Producing Fungus Mortierella alpina 1S-4
- Genetic Analysis of Cytochrome b_5 from Arachidonic Acid-Producing Fungus, Mortierella alpina 1S-4 : Cloning, RNA Editing and Expression of the Gene in Escherichia coli, and Purification and Characterization of the Gene Product^1
- Linoleic Acid Isomerase in Lactobacillus plantarum AKU1009a Proved to Be a Multi-Component Enzyme System Requiring Oxidoreduction Cofactors
- Brassinolide and [26, 28-^2H_6] Brassinolide Are Differently Demethylated by Loss of C-26 and C-28, Respectively, in Marchantia polymorpha
- Synthesis of 4-Hydroxyisoleucine by the Aldolase–Transaminase Coupling Reaction and Basic Characterization of the Aldolase from Arthrobacter simplex AKU 626
- Microbial Production of Optically Active β-Phenylalanine through Stereoselective Degradation of Racemic β-Phenylalanine
- Identification and Characterization of Enzyme Catalyzing Conversion of N^α-Benzyloxycarbonyl-L-Aminoadipic-δ-Semialdehyde to N^α-Benzyloxycarbonyl-L-Aminoadipic Acid in Aspergillus niger AKU 3302(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
- Screening and Industrial Application of Unique Microbial Reactions Involved in Nucleic Acid and Lipid Metabolisms
- Biocatalytic Deprotection of a Cetraxate Ester by Microbacterium sp. Strain 7-1W Cells(Microbiology & Fermentation Technology)
- Changes in Composition and Content of Mycolic Acids in Glutamate-Overproducing Corynebacterium glutamicum
- NAD^+-Dependent (S)-Specific Secondary Alcohol Dehydrogenase Involved in Stereoinversion of 3-Pentyn-2-ol Catalyzed by Nocardia fusca AKU 2123
- Capsaicin-, Resiniferatoxin-, and Olvanil-induced Adrenaline Secretions in Rats via the Vanilloid Receptor(Food & Nutrition Science)
- Pungent Qualities of Sanshool-Related Compounds Evaluated by a Sensory Test and Activation of Rat TRPV1
- Syntheses of Sphingomyelins and Ceramides Bearing a Docosahexaenoyl of Arachidonoyl Group
- Cloning and expression of a cDNA encoding an insoluble matrix protein in the gastroliths of a crayfish, Procambarus clarkii
- Gene Cloning and Functional Analysis of a Second Δ6-Fatty Acid Desaturase from an Arachidonic Acid-producing Mortierella Fungus(Biochemistry & Molecular Biology)
- Glycolic Acid Production Using Ethylene Glycol-Oxidizing Microorganisms(Microbiology & Fermentation Technology)
- Antibacterial Agents that Inhibit Histidine Protein Kinase YycG of Bacillus subtilis(Biochemistry & Molecular Biology)
- Purification and Characterization of a Novel Lactonohydrolase from Agrobacterium tumefaciens
- 1P012 カルボニル還元酵素S1の基質認識機構の構造学的解析(蛋白質-構造,第48回日本生物物理学会年会)
- Newly Synthesized Oleylgingerol and Oleylshogaol Activate TRPV1 Ion Channels
- Distribution of L-Azetidine-2-carboxylate N-Acetyltransferase in Yeast
- Use of Levulinic Acid by Rhodopseudomonas sp. No. 7 for Phototrophic Growth and Enhanced Hydrogen Evolution
- Efficient Production of 2-Deoxyribose 5-Phosphate from Glucose and Acetaldehyde by Coupling of the Alcoholic Fermentation System of Baker's Yeast and Deoxyriboaldolase-Expressing Escherichia coli
- Microbial Production of 2-Deoxyribose 5-Phosphate from Acetaldehyde and Triosephosphate for the Synthesis of 2'-Deoxyribonucleosides(Microbiology & Fermentation Technology)
- Production of Conjugated Fatty Acids by Lactic Acid Bacteria
- Indole Hydroxylation by Bacterial Cytochrome P450 BM-3 and Modulation of Activity by Cumene Hydroperoxide
- アワ種子中に含まれる新規ステロイド、24-Ethyl-5α-cholest-24(28)Z-en-3-oneの合成と同定
- Identification of Brassinosteroids with Epimerized Substituents and/or the 23-Oxo Group in Pollen and Anthers of Japanese Cedar
- Bilirubin Dehydrogenase, an Enzyme in Aspergillus ochraceus IB-3 Useful for Diagnostic Measurement of Bilirubin(Microbiology & Fermentation Technology)
- Identification and Characterization of a Potent Antibacterial Agent, NH125 against Drug-resistant Bacteria
- Enzymatic Properties of an Extracellular Quinoprotein, Enacyloxin Oxidase
- An Extracellular Quinoprotein Oxidase That Catalyzes Conversion of Enacyloxin IVa to Enacyloxin IIa
- Structural Analysis of Conjugated Linoleic Acid Produced by Lactobacillus plantarum, and Factors Affecting Isomer Production(Microbiology & Fermentation Technology)
- Ricinoleic Acid and Castor Oil as Substrates for Conjugated Linoleic Acid Production by Washed Cells of Lactobacillus plantarum(Microbiology & Fermentation Technology)
- Effects of Capsinoid on Serum and Liver Lipids in Hyperlipidemic Rats
- Oleuropein, a Phenolic Compound in Extra Virgin Olive Oil, Increases Uncoupling Protein 1 Content in Brown Adipose Tissue and Enhances Noradrenaline and Adrenaline Secretions in Rats
- Role of Swelling Pressure on the Distribution Coefficient of Maltooligosaccharide in a Cation-exchange Resin(Food & Nutrition)
- Effects of the Divinylbenzene Content and Ionic Form of Cation-exchange Resin on the Chromatographic Separation of Maltooligosaccharides(Food & Nutrition)
- An Enzyme Reactor Based on the Difference in Migration Rate in Gel Chromatographic Columns between Enzyme and Substrate(Biological Chemistry)
- Enzymatic Synthesis of a Capsinoid by the Acylation of Vanillyl Alcohol with Fatty Acid Derivatives Catalyzed by Lipases(Food & Nutrition Science)
- Capsiate, a Nonpungent Capsaicin Analog, Increases Endurance Swimming Capacity of Mice by Stimulation of Vanilloid Receptors
- Administration of Capsiate, a Non-Pungent Capsaicin Analog, Promotes Energy Metabolism and Suppresses Body Fat Accumulation in Mice(Food & Nutrition Science)
- CH-19 Sweet, Nonpungent Cultivar of Red Pepper, Increased Body Temperature in Mice with Vanilloid Receptors Stimulation by Capsiate
- Solubilization and Chemical Characterization of an Insoluble Matrix Protein in the Gastroliths of a Crayfish, Procambarus clarkii
- Purification and Characterization of the Lipase from Pseudomonas fluorescens HU380(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
- Screening and Development of Unique Microbial Functions and Their Industrial Applications
- Exploring Amino Acids Responsible for the Temperature Profile of Glycoside Hydrolase Family 45 Endoglucanase EGL3 from Humicola grisea
- Isolation and Characterization of Inhibitors of the Essential Histidine Kinase, YycG in Bacillus subtilis and Staphylococcus aureus
- Stigmasta-5,25-dien-3β-olおよびstigmasta-5,24(25)-dien-3β-olのsitosterolからの簡便合成
- The Structure of Enacyloxin II, a Novel Linear Polyenic Antibiotic Produced by Gluconobacter sp. W-315(Organic Chemistry)
- Directed evolution of an aminoalcohol dehydrogenase for efficient production of double chiral aminoalcohols(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
- Synthesis of 4-Hydroxyisoleucine by the Aldolase-Transaminase Coupling Reaction and Basic Characterization of the Aldolase from Arthrobacter simplex AKU 626
- A Novel Lipase from Pseudomonas fluorescens HU380: Gene Cloning, Overproduction, Renaturation-Activation, Two-Step Purification, and Characterization(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
- Prenyl Alcohol Production by Expression of Exogenous Isopentenyl Diphosphate Isomerase and Farnesyl Diphosphate Synthase Genes in Escherichia coli
- Suppression of Sourness by Theanine
- Purification and cDNA Cloning of LaIT2, a Novel Insecticidal Toxin from Venom of the Scorpion Liocheles australasiae
- Distribution of L-Azetidine-2-carboxylate N-Acetyltransferase in Yeast
- Assessment of the Biological Similarity of Three Capsaicin Analogs (Capsinoids) Found in Non-Pungent Chili Pepper (CH-19 Sweet) Fruits
- Capsinoids, Non-Pungent Capsaicin Analogs, Reduce Body Fat Accumulation without Weight Rebound unlike Dietary Restriction in Mice
- Linoleic Acid Isomerase in Lactobacillus plantarum AKU1009a Proved to Be a Multi-Component Enzyme System Requiring Oxidoreduction Cofactors
- Biosynthesis and Regulation of Microbial Polyunsaturated Fatty Acid Production
- Cloning and sequencing of a gene encoding of aldehyde oxidase in Pseudomonas sp. AIU 362(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
- Various Oils and Detergents Enhance the Microbial Production of Farnesol and Related Prenyl Alcohols
- Purification and Characterization of a New Aldehyde Oxidase from Pseudomonas sp. AIU 362
- Cloning and sequencing of a gene encoding of aldehyde oxidase in Pseudomonas sp. AIU 362
- Achlorophyllous alga Prototheca zopfii oxidizes n-alkanes with different carbon-chain lengths through a unique subterminal oxidation pathway(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)