Identification and Characterization of a Potent Antibacterial Agent, NH125 against Drug-resistant Bacteria
スポンサーリンク
概要
- 論文の詳細を見る
New imidazole compounds were synthesized to develop a novel and effective antibacterial agent (1-benzyl-3-cetyl-2-methylimidazolium iodide, NH125). In vitro experiments demonstrated that NH125 effectively inhibited a number of different histidine protein kinases. Furthermore, oxacillin-resistant Staphylococcus aureus (ORSA), vancomycin-resistant Enterococcus faecalis (VRE), penicillin-resistant Streptococcus pneumoniae (PRS), and other Gram-positive and Gram-negative bacteria were found to be very sensitive to NH125.
- 社団法人日本農芸化学会の論文
- 2000-04-23
著者
-
WATANABE Tatsuo
School of Food and Nutritional Sciences, University of Shizuoka
-
Yamamoto K
Laboratory Of Insect Genetic Resources Faculty Of Agriculture Kyushu University
-
OKAMOTO Tadashi
Department of Health Sciences and Social Pharmacy, Faculty of Pharmaceutical Sciences, Kobe Gakuin U
-
WATANABE Takafumi
Department of Clinical Biochemistry, Tokyo University of Pharmacy and Life Science
-
KITAYAMA Takashi
Department of Applied Chemistry, Faculty of Engineering, Niigata University
-
Watanabe Tatsuo
Graduate School Of Nutritional And Environmental Sciences And Coe Program In The 21st Century Univ.
-
Kitayama T
Kinki Univ. Nara Jpn
-
Kitayama Takashi
Department Of Applied Chemistry Faculty Of Engineering Niigata University
-
Okamoto T
Hiroshima Univ. Hiroshima Jpn
-
Watanabe T
Department Of Bioscience And Biotechnology Graduate School Of Agriculture Kinki University
-
Yamamoto K
Kyushu Univ. Fukuoka
-
Utsumi Ryutaro
Department of Agricultural Chemistry, Kinki University
-
Tanabe Hiroyuki
Department of Agricultural Chemistry, Kinki University
-
YAMAMOTO Kaneyoshi
Department of Agricultural Chemistry, Kinki University
-
TAKATANI Masahiro
Department of Agricultural Chemistry, Faculty of Agriculture, Kinki University
-
Okamoto Tadashi
Department Of Agricultural Chemistry Faculty Of Agriculture Kinki University
-
Watanabe Tetsuro
Department Of Bioresources Chemistry Chiba University
-
Takatani M
Kinki Univ. Nara Jpn
-
Okamoto T
Department Of Agricultural Chemistry Faculty Of Agriculture Kinki University
-
ISHIDA Noriyasu
Department of Agricultural Chemistry, Kinki University
-
Ishida Noriyasu
Department Of Agricultural Chemistry Kinki University
-
Utsumi R
Department Of Bioscience And Biotechnology Graduate School Of Agriculture Kinki University
-
Utsumi Ryutaro
Department Of Advanced Bioscience Kinki University
-
Watanabe Takafumi
Department Of Aerospace Engineering Osaka Prefecture University
-
Tanabe Hiroyuki
Department Of Agricultural Chemistry Kinki University
-
Tanabe H
Kinki Univ. Nara Jpn
-
WATANABE Toshiro
Fukuoka Agricultural Research Center
-
Kitayama Takashi
Department Of Advanced Bioscience Graduate School Of Agriculture Kinki University
関連論文
- Assessment of the Biological Similarity of Three Capsaicin Analogs (Capsinoids) Found in Non-Pungent Chili Pepper (CH-19 Sweet) Fruits
- Capsinoids, non-pungent capsaicin analogs, reduce body fat accumulation without weight rebound unlike dietary restriction in mice
- Inhibitory Effects of Capsaicinoids on Fatty Acid Desaturation in a Rat Liver Cell Line(Food & Nutrition Science)
- Capsinoids, Non-Pungent Capsaicin Analogs, Reduce Body Fat Accumulation without Weight Rebound unlike Dietary Restriction in Mice
- Brassinolide and [26, 28-^2H_6] Brassinolide Are Differently Demethylated by Loss of C-26 and C-28, Respectively, in Marchantia polymorpha
- Comparison of Uptake between PureSorb-Q^40 and Regular Hydrophobic Coenzyme Q_ in Rats and Humans after Single Oral Intake
- Purification, Molecular Cloning, and Genomic Organization of Human Brain Long-Chain Acyl-CoA Hydrolase
- Rapid Control of Transmembrane Calcium Influx by 1α, 25-Dihydroxyvitamin D_3 and Its Analogues in Rat Osteoblast-Like Cells
- EFFECT OF NICARDIPINE, A CALCIUM ANTAGONIST, ON INDUCTION OF PEROXISOMAL ENZYMES BY DEHYDROEPIANDROSTERONE SULFATE IN CULTURED RAT HEPATOCYTES
- Transcriptional Induction of Acyl-CoA Oxidase by Dehydroepiandrosterone Sulfate in Cultured Rat Hepatocytes
- CHARACTERISTICS OF ENZYME INDUCTION BY PEROXISOME PROLIFERATORS
- Differentially Regulated Genes as Putative Targets of Amplifications at 20q in Ovarian Cancers
- Characterization of superoxide dismutase from the fall webworm, Hyphantria cunea : Comparison of its properties to superoxide dismutase from the silkworm Bombyx mori
- Capsaicin-, Resiniferatoxin-, and Olvanil-induced Adrenaline Secretions in Rats via the Vanilloid Receptor(Food & Nutrition Science)
- Distribution of TNF receptors and TNF receptor-associiated intracellular signaling factors on equine tendinocytes in vitro
- Silkworm Midgut Proteins Interacting with a Hemolymph Protease Inhibitor, CI-8
- Pungent Qualities of Sanshool-Related Compounds Evaluated by a Sensory Test and Activation of Rat TRPV1
- Cloning and expression of a cDNA encoding an insoluble matrix protein in the gastroliths of a crayfish, Procambarus clarkii
- Antibacterial Agents that Inhibit Histidine Protein Kinase YycG of Bacillus subtilis(Biochemistry & Molecular Biology)
- Chemistry of Zerumbone. 2. Regulation of Ring Bond Cleavage and Unique Antibacterial Activities of Zerumbone Derivatives(Organic Chemistry)
- Newly Synthesized Oleylgingerol and Oleylshogaol Activate TRPV1 Ion Channels
- SELECTIVE DESTRUCTION OF ACTIN-BASED CYTOSKELETON NETWORKS IN THE IMMATURE STARFISH OOCYTE BY THEONELLAPEPTOLIDE IE, A PEPTIDE FROM A MARINE SPONGE(Developmental Biology,Abstracts of papers presented at the 74^ Annual Meeting of the Zoological Society
- Malformation of Immature Starfish Oocytes by Theonellapeptolide Ie, a Tridecapeptide Lactone from a Marine Sponge Petrosia Species, through Disturbance of Cortical F-Actin Distribution(Biochemistry & Molecular Biology)
- X-Ray Study of Calcium Phosphates Formed in the Presence of Citrate
- Use of Levulinic Acid by Rhodopseudomonas sp. No. 7 for Phototrophic Growth and Enhanced Hydrogen Evolution
- アワ種子中に含まれる新規ステロイド、24-Ethyl-5α-cholest-24(28)Z-en-3-oneの合成と同定
- Identification of Brassinosteroids with Epimerized Substituents and/or the 23-Oxo Group in Pollen and Anthers of Japanese Cedar
- Inhibitory Effect of Phosphorylated Oligosaccharides Prepared from Potato Starch on the Formation of Calcium Phosphate
- Effective Production of Glycosyl-steviosides by α-1,6 Transglucosylation of Dextrin Dextranase
- Classification of Some α-Glucosidases and α-Xylosidases on the Basis of Substrate Specificity
- Substrate Specificity of Dextrin Dextranase from Acetobacter capsulatus ATCC 11894
- Transfer Action of α-D-Xylosidases from Aspergillus flavus MO-5 on p-Nitrophenyl-α-D-xylopyranoside
- Effective Dextran Production from Starch by Dextrin Dextranase with Debranching Enzyme
- Structure of Dextran Synthesized by Dextrin Dextranase from Acetobacter capsulatus ATCC 11894
- Purification and Characterization of an Intracellular α-D-Xylosidase II from Aspergillus flavus MO-5
- Isolation of Aspergillus flavus MO-5 Producing Two Types of Intracellular α-D-Xylosidases : Purification and Characterization of α-D-Xylosidase I
- Dextran Synthesis from Reduced Maltooligosaccharides by Dextrin Dextranase from Acetobacter capsulatus ATCC 11894
- Detailed Action Mechanism of Dextrin Dextranase from Acetobacter capsulatus ATCC 11894
- Purification and Some Properties of Dextrin Dextranase from Acetobacter capsulatus ATCC 11894
- Effect of adding steam-exploded wood flour to thermoplastic polymer/wood composite
- Identification and Characterization of a Potent Antibacterial Agent, NH125 against Drug-resistant Bacteria
- Enzymatic Properties of an Extracellular Quinoprotein, Enacyloxin Oxidase
- An Extracellular Quinoprotein Oxidase That Catalyzes Conversion of Enacyloxin IVa to Enacyloxin IIa
- Effects of Capsinoid on Serum and Liver Lipids in Hyperlipidemic Rats
- Oleuropein, a Phenolic Compound in Extra Virgin Olive Oil, Increases Uncoupling Protein 1 Content in Brown Adipose Tissue and Enhances Noradrenaline and Adrenaline Secretions in Rats
- Role of Swelling Pressure on the Distribution Coefficient of Maltooligosaccharide in a Cation-exchange Resin(Food & Nutrition)
- Effects of the Divinylbenzene Content and Ionic Form of Cation-exchange Resin on the Chromatographic Separation of Maltooligosaccharides(Food & Nutrition)
- An Enzyme Reactor Based on the Difference in Migration Rate in Gel Chromatographic Columns between Enzyme and Substrate(Biological Chemistry)
- Fundamental studies on wood/cellulose-plastic composites : effects of composition and cellulose dimension on the properties of cellulose/PP composite
- Inhibitory Activity of Alginates against the Formation of Calcium Phosphate
- Trial for linkage mapping of phenotypic characters and EST cDNA clones in the silkworm, Bombyx mori
- Genes Encoding Small Heat Shock Proteins of the Silkworm, Bombyx mori
- Proteomic Studies of Lipopolysaccharide-induced Polypeptides in the Silkworm, Bombyx mori
- In Vivo and in Vitro Interactions of the Bombyx mori Chymotrypsin Inhibitor b1 with Escherichia coli
- Inheritance of a Body Shape Mutant Named "Short Segment" of the Domesticated Silkworm, Bombyx mori
- Overproduction and characterization of hydroxyphenylalanine oxidoreductase of the silkmoth
- Enzymatic Synthesis of a Capsinoid by the Acylation of Vanillyl Alcohol with Fatty Acid Derivatives Catalyzed by Lipases(Food & Nutrition Science)
- Physicochemical Study of Calcium-binding Properties of Chemical Substances as Inhibitors against Calcium Phosphate Insolubilization
- Inhibitory Activity of Oligo- and Poly-L-glutamic Acids against Calcium Phosphate Insolubilization and Calcium Binding with Special Relevance to Their Molecular Weight Dependence
- Capsiate, a Nonpungent Capsaicin Analog, Increases Endurance Swimming Capacity of Mice by Stimulation of Vanilloid Receptors
- Administration of Capsiate, a Non-Pungent Capsaicin Analog, Promotes Energy Metabolism and Suppresses Body Fat Accumulation in Mice(Food & Nutrition Science)
- CH-19 Sweet, Nonpungent Cultivar of Red Pepper, Increased Body Temperature in Mice with Vanilloid Receptors Stimulation by Capsiate
- Superoxide Dismutase from the Silkworm, Bombyx mori : Sequence, Distribution, and Overexpression
- Utility of Dry Gel from Two-dimensional Electrophoresis for Peptide Mass Fingerprinting Analysis of Silkworm Proteins
- Genetic Analysis of Basic Chymotrypsin Inhibitors in the Hemolymph of the Silkworm, Bombyx mori
- Solubilization and Chemical Characterization of an Insoluble Matrix Protein in the Gastroliths of a Crayfish, Procambarus clarkii
- Integration of the twenty-fourth and twenty-seventh linkage groups of the silkwom, Bombyx mori
- Investigation of Integration of Linkage Mapping of Phenotypic Characters and EST cDNA Clones in the Silkworm, Bombyx mori
- Expression and Characterization of a Sigma-Class Glutathione S-Transferase of the Fall Webworm, Hyphantria cunea
- Chymotrypsin and trypsin inhibitors of the saturniid moth, Caligula japonica (Lepidoptera, Saturniidae)
- Purification and characterization of novel Kunitz-type chymotrypsin inhibitor of the silkworm, Bombyx mori
- Basic information for the use of as an experimental animal
- Proteomic Studies of Isoforms of the P25 Component of Bombyx mori Fibroin
- Identification and Overexpression of Y-box Protein Isoform of the Silkworm, Bombyx mori
- Isolation and Molecular Characterization of the Locked-on Mutant of Mg^ Sensor PhoQ in Escherichia coli
- Exploring Amino Acids Responsible for the Temperature Profile of Glycoside Hydrolase Family 45 Endoglucanase EGL3 from Humicola grisea
- Cysteine Uptake for Accumulation of Glutathione by the Cyanobacterium Synechocystis strain PCC 6803
- Isolation and Synthesis of Cosmetic Substances from African Dietary Leaves, Celosia argentea L. for Skin Depigmentation
- Glycosides in the Leaves of African Celosia Argentea L.
- Heart Toxicities: Cultured Myocardial Cell Injury Induced by Adriamycin and Its Regulation
- W4-1 Heart Toxicities : Cultured Myocardial Cell Injury Induced by Adriamycin and Its Regulation
- Structural Properties of Silkworm Small Heat-Shock Proteins : sHSP19.9 and sHSP20.8
- Effect of Intracellular Glutathione on Heat-induced Cell Death in the Cyanobacterium, Synechocystis PCC 6803
- Isolation and Characterization of Inhibitors of the Essential Histidine Kinase, YycG in Bacillus subtilis and Staphylococcus aureus
- Stigmasta-5,25-dien-3β-olおよびstigmasta-5,24(25)-dien-3β-olのsitosterolからの簡便合成
- The Structure of Enacyloxin II, a Novel Linear Polyenic Antibiotic Produced by Gluconobacter sp. W-315(Organic Chemistry)
- Nucleotide Sequence of the Uricase Gene from Bacillus sp. TB-90^1
- Cloning of the Creatinine Amidohydrolase Gene from Pseudomonas sp. PS-7
- Expression and Characterization of a Sigma-Class Glutathione S-Transferase of the Fall Webworm, Hyphantria cunea
- Biosynthesis of Bisorbicillinoid in Trichoderma sp. USF-2690 ; Evidence for the Biosynthetic Pathway, via Sorbicillinol, of Sorbicillin, Bisorbicillinol, Bisorbibutenolide, and Bisorbicillinolide(Organic Chemistry)
- Novel Fungal Metabolites, Demethylsorbicillin and Oxosorbicillinol, Isolated from Trichoderma sp. USF-2690
- Effects of Acetylenes and Terpenoids from Solidago altissima L. on Seed Germination
- Dehydromatricariaラクトン類のZ体およびE体のキャラクタリゼ-ション
- B/E Constant Linked Scan Fast Atom Bombardment Analysis of a New Type of Glycosyl Phosphosphingolipid Isolated from Edible Fungi (Mushroom)
- Suppression of Sourness by Theanine
- Assessment of the Biological Similarity of Three Capsaicin Analogs (Capsinoids) Found in Non-Pungent Chili Pepper (CH-19 Sweet) Fruits
- Capsinoids, Non-Pungent Capsaicin Analogs, Reduce Body Fat Accumulation without Weight Rebound unlike Dietary Restriction in Mice
- Development of room-temperature curing aqueous emulsion-type acrylic adhesive II : effect of monomer composition on the final adhesive strength
- Development of room-temperature curing aqueous emulsion-type acrylic adhesive I : effect of monomer composition on the initial adhesive strength
- Transcription of emrKY is Regulated by the EvgA-EvgS Two-Component System in Escherichia coli K-12