Safety Evaluation of Flavonoids-Containing Tomato Skin Extract

スポンサーリンク

概要

• 論文の詳細を見る
• 2004-11-30

著者

• Sakai Takafumi

  Division Of Applied Life Sciences Graduate School Of Agriculture Kyoto University

• Takahashi S

  Cancer Prevention Basic Research Project National Cancer Center Research Institute

• Sawa T

  Institute Of Microbial Chemistry

• Sakai T

  Kyoto Univ. Kyoto Jpn

• YAMAKOSHI Jun

  Research and Development Division, Kikkoman Corporation

• SATO Takuya

  Research and Development Division, Kikkoman Corporation

• MATSUURA Katsuko

  Research and Development Division, Kikkoman Corporation

• YAMAMOTO Taichi

  Research and Development Division, Kikkoman Corporation

• OBATA Akio

  Research and Development Division, Kikkoman Corporation

• SAITO Makoto

  Research and Development Division, Kikkoman Corporation

• MATSUYAMA Asahi

  Research and Development Division, Kikkoman Corporation

• KIKUCHI Mamoru

  Research and Development Division, Kikkoman Corporation

• Saito Makoto

  Research And Development Division Kikkoman Corporation

• Saito M

  Department Of Biotechnology And Life Science Tokyo University Of Agriculture And Technology

• 松浦 克子

  キッコーマン株式会社 研究本部

• Kikuchi Masanori

  Department Of Food Production And Utility Development Graduate School Of Dairy Science Research Raku

• Obata A

  Kikkoman Corp. Chiba Jpn

• Obata Akio

  Research & Development Division Kikkoman Corporation

• Kikuchi M

  Kikkoman Corp. Chiba Jpn

• Yamakoshi Jun

  Research And Development Division Kikkoman Corporation

• Kikuchi Mamoru

  Res. And Dev. Div. Kikkoman Corp.

• Kikuchi Mamoru

  Research & Development Division Kikkoman Corporation

• Mori K

  Sci. Univ. Tokyo Tokyo Jpn

• Shimokawa Takashi

  Natl. Inst. Radiol. Sci.

• Kikuchi M

  Res. And Dev. Div. Kikkoman Corp.

• Saito M

  Research And Development Division Kikkoman Corporation

• Matsuyama Asahi

  Research And Development Division Kikkoman Corporation

• Yamamoto Taichi

  Department Of Applied Molecular Biosciences Graduate School Of Bioagricultural Sciences Nagoya Unive

• Yamamoto Taichi

  Research & Development Division Kikkoman Corporation

• Yamakoshi J

  Research And Development Division Kikkoman Corporation

• Tamai Susumu

  Cancer Prevention Division National Cancer Center Research Institute

• Sugimura Takashi

  Carcinogenesis Division National Cancer Center Research Institute

• Saito Makoto

  Research & Development Division Kikkoman Corporation

• Sasaki Takayuki

  Institute Of Plant Science And Resources Okayama University

関連論文

• Helicobacter pylori Infection, Serum Pepsinogen Level and Gastric Cancer : A Case-Control Study in Japan
• Frequent hypomethylation in multiple promoter CpG islands is associated with global hypomethylation, but not with frequent promoter hypermethylation
• Cloning of the 5' Upstream Region of the Rat p16 Gene and Its Role in Silencing
• Inhibition of cell proliferation by nobiletin, a dietary phytochemical, associated with apoptosis and characteristic gene expression, but lack of effect on early rat hepatocarcinogenesis in vivo
• Periodic analysis of urethane-induced pulmonary tumors in living A/J mice by respiration-gated X-ray microcomputed tomography
• Induction of multinucleated cells and apoptosis in the PC-3 prostate cancer cell line by low concentrations of polyethylene glycol 1000
• Mouse strain differences in inflammatory responses of colonic mucosa induced by dextran sulfate sodium cause differential susceptibility to PhIP-induced large bowel carcinogenesis
• Toxicogenomic approach to the prediction of carcinogenic potentials of heterocyclic amines in rat colon(Analysis of Toxicological Mechanisms : A Toxicogenomics Approach, Proceedings of the 32nd Annual Meeting)
• HETEROCYCLIC AMINES : MUTAGENS/CARCINOGENS PRODUCED DURING COOKING OF MEAT AND FISH
• Heterocyclic amines : Mutagens/carcinogens produced during cooking of meat and fish
• Differential gene expression profiles in colon epithelium of two rat strains with distinct susceptibility to colon carcinogenesis after exposure to PhlP in combination with dietary high fat
• Parp-1 deficiency implicated in colon and liver tumorigenesis induced by azoxymethane
• Induction of Intestinal Tumors and Lymphomas in C57BL/6N Mice by a Food-borne Carcinogen, 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
• Frequent and Multiple Mutations at Minisatellite Loci in Sporadic Human Colorectal and Gastric Cancers : Possible Mechanisble Mechanistic Differences from Microsatellite Instability in Cancer Cells
• Migrastatin, a Novel 14-Membered Lactone from Streptomyces sp. MK929-43F1
• Lactonamycin, a New Antimicrobial Antibiotic Produced by Streptomyces rishiriensis MJ773-88K4 II. Structure Determination
• Lactonamycin, a New Antimicrobial Antibiotic Produced by Streptomyces rishiriensis MJ773-88K4 I. Taxonomy, Fermentation, Isolation, Physico-chemical properties and Biological Activities
• Biosynthesis of Neothramycin
• Kinetic Studies on p-Nitrophenyl-cellobioside Hydrolyzing Xylanase from Cellvibrio gilvus
• Phosphorolytic Reaction of Cellvibrio gilvus Cellobiose Phosphorylase
• Purification and Properties of a Xylanase from Cellvibrio gilvus That Hydrolyzes p-Nitrophenyl Cellooligosaccharides(Biological Chemistry)
• Synthesis of Laminarioligosaccharides Using Crude Extract of Euglena gracilis z Cells(Biological Chemistry)
• A Simple Method of Cellulase Immobilization on a Modified Silica Support
• Safety Evaluation of Flavonoids-Containing Tomato Skin Extract
• Occurrence of mutations in the epidermal growth factor receptor gene in X-ray-induced rat lung tumors
• Phylogenic distribution of poly(ADP-ribose) glycohydrolase and poly(ADP-ribose)-digesting phosphodiesterase
• Isolation and Cloning of Rat Poly (ADP-Ribose) Glycohydrolase: Presence of a Potential Nuclear Export Signal Conserved in Mammalian Orthologs
• Presence in Pieris rapae of Cytotoxic Activity against Human Carcinoma Cells
• PHYSIOLOGYCAL ROLE OF A APOPTOSIS-INDUCING PROTEIN, PIERISIN-1, IN CABBAGE BUTTERFLY, PIERIS RAPAE(Endocrinology,Abstracts of papers presented at the 76^ Annual Meeting of the Zoological Society of Japan)
• Pressure Distribution Measurement in Biting Surimi Gels with Molars Using a Multiple-point Sheet Sensor(Food & Nutrition Science)
• Patterns Observed in the First Chew of Foods with Various Textures
• Purification of Pierisin, an Inducer of Apoptosis in Human Gastric Carcinoma Cells, from Cabbage Butterfly, Pieris rapae
• Detection of endogenous DNA adducts, O^6-carboxymethyl-2'-deoxyguanosine and 3-ethanesulfonic acid-2'-deoxycytidine, in the rat stomach after duodenal reflux
• Enzymatic Properties of Pierisin-1 and Its N-Terminal Domain, a Guanine-Specific ADP-Ribosyltransferase from the Cabbage Butterfly
• Detection and Cloning of a Protein Recognized by Anti-human Prostate-specific Antigen (PSA) Antibody in the Rat Ventral Prostate
• Necessity of dietary taurine supplementation for preventing green liver symptom and improving growth performance in yearling red sea bream Pagrus major fed nonfishmeal diets based on soy protein concentrate
• Synthesis of 4-Hydroxy-3(2H)-furanone Acyl Derivatives and Their Anti-cataract Effect on Spontaneous Cataract Rats (ICR/f)
• Antioxidative Activities of 4-Hydroxy-3 (2H)-furanones and Their Anti-cataract Effect on Spontaneous Cataract Rat (ICR/f)
• Induction of GM-CSF Production of Macrophages by Advanced Glycation End Products of the Maillard Reaction
• The Effects of Interleukin (IL)-4 and IL-10 on Macrophage Growth-Stimulating Activities of Oxidized Low Density Lipoprotein (LDL), Acetylated LDL and Macrophage Colony-Stimulating Factor : The activity of Oxidized LDL Is Refractory to the Inhibitory Cytok
• Stimulation of Macrophage DNA Synthesis by Polyanionic Substances through Binding to the Macrophage Scavenger Receptor
• Migrastatin, a New Inhibitor of Tumor Cell Migration from Streptomyces sp. MK929-43F1 : Taxonomy, Fermentation, Isolation and Biological Activities
• Genetically engineered Bifidobacterium longum for tumor-targeting enzyme-prodrug therapy of autochthonous mammary tumors in rats
• Cloned Cytosine Deaminase Gene Expression of Bifidobacterium longum and Application to Enzyme/Pro-drug Therapy of Hypoxic Solid Tumors(Biochemistry & Molecular Biology)
• Inhibition of Rat Embryo Histidine Decarboxylase by Epoxyquinomicins
• MK800-62F1, a New Inhibitor of Apoptotic Cell Death, from Streptomyces diastatochromogenes MK800-62F1 : II. Structure Elucidation
• MK800-62F1, a New Inhibitor of Apoptotic Cell Death, from Streptomyces diastatochromogenes MK800-62F1 : I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activity
• C-1027 Enediyne Chromophore: Presence of Another Active Form and Its Chemical Structure
• Diperamycin, a New Antimicrobial Antibiotic Produced by Streptomyces griseoaurantiacus MK393-AF2 I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activities
• MJ347-81F4 A & B, Novel Antibiotics from Amycolatopsis sp.: Taxonomic Characteristics, Fermentation, and Antimicrobial Activity
• Effect of a Novel Antibiotic, Heliquinomycin, on DNA Helicase and Cell Growth
• Cremimycin, a Novel 19-Membered Macrocyclic Lactam Antibiotic, from Streptomyces sp.
• Epoxyquinomicins A, B, C and D, New Antibiotics from Amycolatopsis III. Physico-chemical Properties and Structure Determination
• Epoxyquinomicins A, B, C and D, New Antibiotics from Amycolatopsis II. Effect on Type II Collagen-induced Arthritis in Mice
• Epoxyquinomicins A, B, C and D, New Antibiotics from Amycolatopsis I. Taxonomy, Fermentation, Isolation and Antimicrobial Activities
• Discovery of Methyl-2-(2'-hydroxyphenyl)-2-oxazoline-4-carboxylate as a Secondary Metabolite from Actinomadura sp.
• Heliquinomycin, a New Inhibitor of DNA Helicase, Produced by Streptomyces sp. MJ929-SF2 III. Biosynthesis
• A New Anthracycline Antibiotic, IT-62-B, Converts the Morphology of ras-Transformed Cells Back to Normal: Taxonomy, Fermentation, Isolation, Structure Elucidation and Biological Characterization
• Pyralomicins, Novel Antibiotics from Microtetraspora spiralis IV. Absolute Configuration
• Imaging study of pancreatic ductal adenocarcinomas in Syrian hamsters using X-ray micro-computed tomography (CT)
• Effects of α-Tocopherol Levels in Extrusion Pellets on In vivo Lipid Peroxidation Levels and Antioxidant Activities in Cultured Yellowtail Seriola quinqueradiata Injected with the Causative Bacteria of Fish Jaundice
• The Oxidation State and Its Distribution of Selenium in the Blood of Cultured Yellow Tail Seriora Quinqueradiata
• Suppression of azoxymethane-induced colon cancer development in rats by a cyclooxygenase-1 selective inhibitor, mofezolac
• Inhibition of intestinal carcinogenesis by a new flavone derivative, chafuroside, in oolong tea
• Cloning of Mongolian gerbil cDNAs encoding inflammatory proteins, and their expression in glandular stomach during H. pylori infection
• Dose-dependent suppression of hyperlipidemia and intestinal polyp formation in Min mice by pioglitazone, a PPARγ ligand
• The Absence of Mth1 Inactivation and DNA Polymerase κ Overexpression in Rat Mammary Carcinomas with Frequent A:T to C:G Transversions
• Linkage Mapping of the Rat Interleukin 1 Receptor Antagonist Gene on Chromosome 3
• UV-lnduced Apoptosis in Thymic Lymphoma Cells : Cell Cycle uependency.
• Effects of Serine Protease Inhibitors on the Radiation-induced Apoptosis in Thymocytes and Lymphoma Cells.
• Hemolytic suppression roles of taurine in yellowtail Seriola quinqueradiata fed non-fishmeal diet based on soybean protein
• Manufacturing High Purity Maltose and Maltotetraose from Starch by a Novel and Efficient Procedure Named "Reducing End Modification Method"
• Effects of Moranoline, 4-O-α-D-Glucopyranosylmoranoline and Their N-Substituted Derivatives on Thermostability of Cyclodextrin Glycosyltransferase, Glucoamylase, and β-Amylase
• Studies on the green liver in cultured red sea bream fed low level and non-fish meal diets : Relationship between hepatic taurine and biliverdin levels
• High-performance liquid chromatographic analysis of ascorbyl-2-phosphate in fish tissues
• In vivo Lipid Peroxidation Levels and Antioxidant Activities of Cultured and Wild Yellowtail
• Simultaneous determination of ascorbic acid and dehydroascorbic acid in fish tissues by high-performance liquid chromatography
• Glutathione Peroxidase Activity in the Blood of Tunas and Marlins
• Occurrence of Hyperbilirubinemia in Cultured Red Sea Bream
• 2-Thiobarbituric Acid Values and Contents of α-Tocopherol and Bile Pigments in the Liver and Muscle of Jaundiced Yellowtail, Seriola quinqueradiata(Biological Chemistry)
• Efficient Production of 2-Deoxyribose 5-Phosphate from Glucose and Acetaldehyde by Coupling of the Alcoholic Fermentation System of Baker's Yeast and Deoxyriboaldolase-Expressing Escherichia coli
• Microbial Production of 2-Deoxyribose 5-Phosphate from Acetaldehyde and Triosephosphate for the Synthesis of 2'-Deoxyribonucleosides(Microbiology & Fermentation Technology)
• Secondary Emission in NaNO_2 under Selective Excitation:Dispersion and Relaxation of ν_ Exciton
• Relationships between 4-Hydroxy-2-nonenal, 2-Thiobarbituric Acid Reactive Substances and n-6 Polyunsaturated Fatty Acids in Refrigerated and Frozen Pork
• Enzymatic Synthesis of 4-O-β-D-Galactopyranosyl-moranoline and 3-O-β-D-Galacto-pyranosyl-moranoline by Using β-Galactosidase from Bacillus circulans
• A Lipid Peroxidation-derived Aldehyde, 4-Hydroxy-2-nonenal and ω6 Fatty Acids Contents in Meats
• Isolation of 2-Amino-2-deoxy-D-mannitol from Culture Broth of Streptomyces species(Microbiology & Fermentation Industry)
• Enzymatic Synthesis of Stable, Odorless, and Powdered Furanone Glucosides by Sucrose Phosphorylase
• Closing Plant Stomata Requires a Homolog of an Aluminum-Activated Malate Transporter
• Measurement of Contractile Activity in Small Animal's Digestive Organ by Carbon Nanotube-Based Force Transducer
• Antihypertensive and Natriuretic Effects of Less-Sodium Soy Sauce Containing γ-Aminobutyric Acid in Spontaneously Hypertensive Rats
• Biliary Bile Salts Reduction in Red Sea Bream Fed on Soybean Meal Diet
• Targeting solid tumors with non-pathogenic obligate anaerobic bacteria
• Exogeneous Cytosine Deaminase Gene Expression in Bifidobacterium breve I-53-8w for Tumor-Targeting Enzyme/Prodrug Therapy
• Strong Enhancement of Recombinant Cytosine Deaminase Activity in Bifidobacterium longum for Tumor-Targeting Enzyme/Prodrug Therapy
• Role of taurine deficiency in inducing green liver symptom and effect of dietary taurine supplementation in improving growth in juvenile red sea bream Pagrus major fed non-fishmeal diets based on soy protein concentrate
• Determination of hepatic cysteinesulfinate decarboxylase activity in fish by means of OPA-prelabeling and reverse-phase high-performance liquid chromatographic separation
• Chemical Modification of Carbon Nanotube Based Bio-Nanosensor by Plasma Activation
• Inhibitory Effects of Methylglyoxal on Light-Induced Stomatal Opening and Inward K^+ Channel Activity in Arabidopsis
• Paleic acid, a fatty acid from Paenibacillus sp. : taxonomy, fermentation, isolation, structure determination, and anti-Mannheimia and-Pasteurella activity

もっと見る 閉じる

スポンサーリンク