C-1027 Enediyne Chromophore: Presence of Another Active Form and Its Chemical Structure
スポンサーリンク
概要
- 論文の詳細を見る
- 1999-04-25
著者
-
Sawa T
Institute Of Microbial Chemistry
-
Shimokawa Takashi
国立がんセンター
-
OTANI Toshio
Tokushima Research Center, Taiho Pharmaceutical Co., Ltd.
-
YOSHIDA Ken-ichiro
Tokushima Research Center. Taiho Pharmaceutical Co., Ltd.
-
SASAKI Toru
Tokushima Research Center, Taiho Pharmaceutical Co. Ltd.
-
MINAMI Yoshinori
Tokushima Research Center, Taiho Pharmaceutical Co. Ltd.
-
Yoshida Ken-ichiro
Tokushima Research Center Taiho Pharmaceutical Co. Ltd.
-
Otani T
Tokushima Research Center Taiho Pharmaceutical Co. Ltd.
-
Otani Toshio
Tokushima Research Center Taiho Pharmaceutical Co. Ltd.
-
Tamai Susumu
Cancer Prevention Division National Cancer Center Research Institute
-
Sasaki Toru
Tokushima Research Center Taiho Pharmaceutical Co. Ltd.
-
Minami Yoshinori
Tokushima Research Center Taiho Pharmaceutical Co. Ltd.
関連論文
- Frequent hypomethylation in multiple promoter CpG islands is associated with global hypomethylation, but not with frequent promoter hypermethylation
- Cloning of the 5' Upstream Region of the Rat p16 Gene and Its Role in Silencing
- Periodic analysis of urethane-induced pulmonary tumors in living A/J mice by respiration-gated X-ray microcomputed tomography
- Induction of multinucleated cells and apoptosis in the PC-3 prostate cancer cell line by low concentrations of polyethylene glycol 1000
- Mouse strain differences in inflammatory responses of colonic mucosa induced by dextran sulfate sodium cause differential susceptibility to PhIP-induced large bowel carcinogenesis
- Toxicogenomic approach to the prediction of carcinogenic potentials of heterocyclic amines in rat colon(Analysis of Toxicological Mechanisms : A Toxicogenomics Approach, Proceedings of the 32nd Annual Meeting)
- HETEROCYCLIC AMINES : MUTAGENS/CARCINOGENS PRODUCED DURING COOKING OF MEAT AND FISH
- Heterocyclic amines : Mutagens/carcinogens produced during cooking of meat and fish
- Differential gene expression profiles in colon epithelium of two rat strains with distinct susceptibility to colon carcinogenesis after exposure to PhlP in combination with dietary high fat
- Parp-1 deficiency implicated in colon and liver tumorigenesis induced by azoxymethane
- Induction of Intestinal Tumors and Lymphomas in C57BL/6N Mice by a Food-borne Carcinogen, 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
- Frequent and Multiple Mutations at Minisatellite Loci in Sporadic Human Colorectal and Gastric Cancers : Possible Mechanisble Mechanistic Differences from Microsatellite Instability in Cancer Cells
- Linkage Mapping of the Bra, Brb and Brg Genes for Rat Protein Phosphatase 2A 55 kDa B-Regulatory Subunit Isotypes
- Helicobacter pylori Extracts Exhibit Nicotinamide Adenine Dinucleotide-derived Adenylation but Not Mono(adenosine 5'-diphosphate-ribosyl)ation of DNA Ligase
- Chemoprevention by Nimesulide, a Selective Cyclooxygenase-2 Inhibitor, of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine(PhIP)-induced Mammary Gland Carcinogenesis in Rats
- Telomerase Activity Correlates with Growth of Transplantable Osteosarcomas in Rats Treated with cis-Diammine Dichloroplatinum or the Angiogenesis Inhibitor AGM-1470
- Migrastatin, a Novel 14-Membered Lactone from Streptomyces sp. MK929-43F1
- Lactonamycin, a New Antimicrobial Antibiotic Produced by Streptomyces rishiriensis MJ773-88K4 II. Structure Determination
- Lactonamycin, a New Antimicrobial Antibiotic Produced by Streptomyces rishiriensis MJ773-88K4 I. Taxonomy, Fermentation, Isolation, Physico-chemical properties and Biological Activities
- Biosynthesis of Neothramycin
- Kinetic Studies on p-Nitrophenyl-cellobioside Hydrolyzing Xylanase from Cellvibrio gilvus
- Phosphorolytic Reaction of Cellvibrio gilvus Cellobiose Phosphorylase
- Purification and Properties of a Xylanase from Cellvibrio gilvus That Hydrolyzes p-Nitrophenyl Cellooligosaccharides(Biological Chemistry)
- Synthesis of Laminarioligosaccharides Using Crude Extract of Euglena gracilis z Cells(Biological Chemistry)
- A Simple Method of Cellulase Immobilization on a Modified Silica Support
- Safety Evaluation of Flavonoids-Containing Tomato Skin Extract
- Occurrence of mutations in the epidermal growth factor receptor gene in X-ray-induced rat lung tumors
- Isolation and Cloning of Rat Poly (ADP-Ribose) Glycohydrolase: Presence of a Potential Nuclear Export Signal Conserved in Mammalian Orthologs
- Linkage Maping of the Rat Poly(ADP-ribose) Glycohydrolase (Parg) Gene to Chromosome 16
- PHYSIOLOGYCAL ROLE OF A APOPTOSIS-INDUCING PROTEIN, PIERISIN-1, IN CABBAGE BUTTERFLY, PIERIS RAPAE(Endocrinology,Abstracts of papers presented at the 76^ Annual Meeting of the Zoological Society of Japan)
- Difference in Target Organs in Carcinogenesis with a Heterocyclic Amine, 2-Amino-3,4-dimethylimidazo[4,5-f]quinoline, in Different Strains of Mice
- Linkage Mapping of the Rat Msh2 DNA Mismatch Repair Gene on Chromosome 6
- Inhibition of Anchorage-Independent Growth of Tumor Cells by IT-62-B, a New Anthracycline
- Novel Triene-β-lactone Antibiotics, Oxazolomycin Derivative and Its Isomer, Produced by Streptomyces sp. KSM-2690
- Purification of Pierisin, an Inducer of Apoptosis in Human Gastric Carcinoma Cells, from Cabbage Butterfly, Pieris rapae
- Possible Lack of Carcinogenic Potential of 9-(4'-Aminophenyl)-9H-pyrido[3,4-b]indole (aminophenylnorharman) for the Pancreatic Duct Epithelium in Hamsters
- Detection of endogenous DNA adducts, O^6-carboxymethyl-2'-deoxyguanosine and 3-ethanesulfonic acid-2'-deoxycytidine, in the rat stomach after duodenal reflux
- Enzymatic Properties of Pierisin-1 and Its N-Terminal Domain, a Guanine-Specific ADP-Ribosyltransferase from the Cabbage Butterfly
- Detection and Cloning of a Protein Recognized by Anti-human Prostate-specific Antigen (PSA) Antibody in the Rat Ventral Prostate
- Suppression by Flavonoids of Cyclooxygenase-2 Promoter-dependent Transcriptional Activity in Colon Cancer Cells: Structure-Activity Relationship
- Effects of a Soybean Isoflavone Mixture on Carcinogenesis in Prostate and Seminal Vesicles of F344 Rats
- Suppression of Intestinal Polyp Development by Nimesulide, a Selective Cyclooxygenase-2 Inhibitor, in Min Mice
- Suppression of Nitric Oxide Production in Lipopolysaccharide-stimulated Macrophage Cells by ω3 Polyunsaturated Fatty Acids
- Induction of GM-CSF Production of Macrophages by Advanced Glycation End Products of the Maillard Reaction
- The Effects of Interleukin (IL)-4 and IL-10 on Macrophage Growth-Stimulating Activities of Oxidized Low Density Lipoprotein (LDL), Acetylated LDL and Macrophage Colony-Stimulating Factor : The activity of Oxidized LDL Is Refractory to the Inhibitory Cytok
- Stimulation of Macrophage DNA Synthesis by Polyanionic Substances through Binding to the Macrophage Scavenger Receptor
- Migrastatin, a New Inhibitor of Tumor Cell Migration from Streptomyces sp. MK929-43F1 : Taxonomy, Fermentation, Isolation and Biological Activities
- 21WA-03-3 In Vivo Toxicity of Aminophenylnorharman, a Product from the Reaction of Norharman and Aniline, in F344 Rats.
- Genetically engineered Bifidobacterium longum for tumor-targeting enzyme-prodrug therapy of autochthonous mammary tumors in rats
- Cloned Cytosine Deaminase Gene Expression of Bifidobacterium longum and Application to Enzyme/Pro-drug Therapy of Hypoxic Solid Tumors(Biochemistry & Molecular Biology)
- Inhibition of Rat Embryo Histidine Decarboxylase by Epoxyquinomicins
- MK800-62F1, a New Inhibitor of Apoptotic Cell Death, from Streptomyces diastatochromogenes MK800-62F1 : II. Structure Elucidation
- MK800-62F1, a New Inhibitor of Apoptotic Cell Death, from Streptomyces diastatochromogenes MK800-62F1 : I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activity
- C-1027 Enediyne Chromophore: Presence of Another Active Form and Its Chemical Structure
- Diperamycin, a New Antimicrobial Antibiotic Produced by Streptomyces griseoaurantiacus MK393-AF2 I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activities
- MJ347-81F4 A & B, Novel Antibiotics from Amycolatopsis sp.: Taxonomic Characteristics, Fermentation, and Antimicrobial Activity
- Effect of a Novel Antibiotic, Heliquinomycin, on DNA Helicase and Cell Growth
- Cremimycin, a Novel 19-Membered Macrocyclic Lactam Antibiotic, from Streptomyces sp.
- Epoxyquinomicins A, B, C and D, New Antibiotics from Amycolatopsis III. Physico-chemical Properties and Structure Determination
- Epoxyquinomicins A, B, C and D, New Antibiotics from Amycolatopsis II. Effect on Type II Collagen-induced Arthritis in Mice
- Epoxyquinomicins A, B, C and D, New Antibiotics from Amycolatopsis I. Taxonomy, Fermentation, Isolation and Antimicrobial Activities
- Discovery of Methyl-2-(2'-hydroxyphenyl)-2-oxazoline-4-carboxylate as a Secondary Metabolite from Actinomadura sp.
- Heliquinomycin, a New Inhibitor of DNA Helicase, Produced by Streptomyces sp. MJ929-SF2 III. Biosynthesis
- A New Anthracycline Antibiotic, IT-62-B, Converts the Morphology of ras-Transformed Cells Back to Normal: Taxonomy, Fermentation, Isolation, Structure Elucidation and Biological Characterization
- Pyralomicins, Novel Antibiotics from Microtetraspora spiralis IV. Absolute Configuration
- Heliquinomycin, a New Inhibitor of DNA Helicase, Produced by Streptomyces sp. MJ929-SF2 II. Structure Determination of Heliquinomycin
- Inhibition of Spontaneous Rat Osteosarcoma Lung Metastasis by 3S-[4-(Nhydroxyamino)-2R-isobutylsuccinyl]-1-methoxy-3,4-dihydrocarbostyril, a Novel Matrix Metalloproteinase Inhibitor
- Imaging study of pancreatic ductal adenocarcinomas in Syrian hamsters using X-ray micro-computed tomography (CT)
- Suppression of azoxymethane-induced colon cancer development in rats by a cyclooxygenase-1 selective inhibitor, mofezolac
- Inhibition of intestinal carcinogenesis by a new flavone derivative, chafuroside, in oolong tea
- Cloning of Mongolian gerbil cDNAs encoding inflammatory proteins, and their expression in glandular stomach during H. pylori infection
- Dose-dependent suppression of hyperlipidemia and intestinal polyp formation in Min mice by pioglitazone, a PPARγ ligand
- The Absence of Mth1 Inactivation and DNA Polymerase κ Overexpression in Rat Mammary Carcinomas with Frequent A:T to C:G Transversions
- Linkage Mapping of the Rat Interleukin 1 Receptor Antagonist Gene on Chromosome 3
- Combined effects of prostaglandin E receptor subtype EP_1 and subtype EP_4 antagonists on intestinal tumorigenesis in adenomatous polyposis coli gene knockout mice
- Marked Enhancement by Fish Meal of Helicobacter pylori-induced Gastritis in Mongolian Gerbils
- Caprazamycins, Novel Lipo-nucleoside Antibiotics, from Streptomyces sp : II. Structure Elucidation of Caprazamycins
- IT-143-A and B, Novel Piericidin-group Antibiotics Produced by Streptomyces sp.
- Analysis or Radioresistant Variants Derived from 3SB Cell
- Cloning and Nucleotide Sequencing of the Antitumor Antibiotic C-1027 Apoprotein Gene
- Closing Plant Stomata Requires a Homolog of an Aluminum-Activated Malate Transporter
- Inhibition of poly(ADP-ribose) glycohydrolase activity by cyclic peptide antibiotics containing piperazic acid residues
- Phylogenic distribution of poly(ADP-ribose) glycohydrolase and poly(ADP-ribose)-digesting phosphodiesterase
- Structure-Activity Relationships between Linkage Style at the C-3 Position and Nuclear Analogues of C(7)-Hydroxyminoaminothiazol Cephalosporins against Methicillin-Resistant Staphylococcus aureus
- Structure-Activity Relationships of 2-Thioisocephem against Methicillin-resistant Staphylococcus aureus
- Antihypertensive and Natriuretic Effects of Less-Sodium Soy Sauce Containing γ-Aminobutyric Acid in Spontaneously Hypertensive Rats
- Targeting solid tumors with non-pathogenic obligate anaerobic bacteria
- Exogeneous Cytosine Deaminase Gene Expression in Bifidobacterium breve I-53-8w for Tumor-Targeting Enzyme/Prodrug Therapy
- Strong Enhancement of Recombinant Cytosine Deaminase Activity in Bifidobacterium longum for Tumor-Targeting Enzyme/Prodrug Therapy
- The Nucleotide Sequence of the β-Glucosidase Gene from Cellvibrio gilvus
- The Nucleotide Sequence of the β-Glucosidase Gene from Cellvibrio gilvus
- Characterization of a β-Glucosidase Encoded by a Gene from Cellvibrio gilvus(Biological Chemistry)
- Azicemicins A and B, New Antimicrobial Agent Produced by Amycolatopsis:I.Taxonomy, Fermentation, Isolation, Characterization and Biological Activities
- Inhibitory Effects of Methylglyoxal on Light-Induced Stomatal Opening and Inward K^+ Channel Activity in Arabidopsis
- Paleic acid, a fatty acid from Paenibacillus sp. : taxonomy, fermentation, isolation, structure determination, and anti-Mannheimia and-Pasteurella activity