Antioxidative Activities of 4-Hydroxy-3 (2H)-furanones and Their Anti-cataract Effect on Spontaneous Cataract Rat (ICR/f)
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概要
- 論文の詳細を見る
We determined the anti-cataract effects and antioxidative activities of four 4-hydroxy-3 (2H)-furanones. These four furanones showed similar antioxidative activities in the ferric ion reduction model. 4-Hydroxy-2,5-dimethyl-3 (2H)-furanone (HDMF) and 2 (or 5)-ethyl-4-hydroxy-5 (or 2)-methyl-3 (2H)-furanone (EHMF) exhibited a higher suppression effect on lipid peroxidation in human plasma than the other furanones did. The effects of hydroxy furanones on the onset of cataract in spontaneous cataract rat (ICR/f rat) were tested, and it was observed that HDMF and EHMF inhibited cataract formation. These results suggest that the antioxidative activity of HDMF and EHMF against superoxide radicals in lens tissue contributed to inhibiting the onset of spontaneous cataract.
- 社団法人日本農芸化学会の論文
- 1998-10-23
著者
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Sakai Takafumi
Division Of Applied Life Sciences Graduate School Of Agriculture Kyoto University
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Sakai T
Kyoto Univ. Kyoto Jpn
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YAMAKOSHI Jun
Research and Development Division, Kikkoman Corporation
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SAITO Makoto
Research and Development Division, Kikkoman Corporation
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Mori Kenji
Department of Biochemistry, National Cardiovascular Center Research Institute
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Sakai T
Kikkoman Corp. Chiba Jpn
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KASAI Kouichi
Research and Development Division, Kikkoman Corporation
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Saito Makoto
Research And Development Division Kikkoman Corporation
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Kasai K
Research And Development Division Kikkoman Corporation
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Kasai Kouichi
Research And Development Division Kikkoman Corporation
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Koga Takuro
Biochemical Division Kikkoman Corporation
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Koga Takuro
Noda Institute For Scientific Research
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松浦 克子
キッコーマン株式会社 研究本部
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SASAKI Tsutomu
Research and Development Division, Kikkoman Corporation
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MATSUDO Takanao
Research and Development Division, Kikkoman Corporation
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Matsudo T
Kikkoman Corp. Chiba Jpn
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Matsudo Takanao
Research And Development Division Kikkoman Corporation
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Takagi S
Ehime Prefectural Fisheries Experimental Station
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Koga T
National Institute Of Advanced Industrial Science And Technology
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Yamakoshi Jun
Research And Development Division Kikkoman Corporation
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Mori K
Sci. Univ. Tokyo Tokyo Jpn
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Saito M
Research And Development Division Kikkoman Corporation
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Yamakoshi J
Research And Development Division Kikkoman Corporation
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Mori Kenji
Department Of Biochemistry National Cardiovascular Center Research Institute
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Mori Kenji
Department Of Agricultural Chemistry The University Of Tokyo
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Mori Kenji
Department Of Agricultural Chemistry Nagoya University
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Saito Makoto
Research & Development Division Kikkoman Corporation
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Mori Kenji
Department Of Agricultural Chemistry College Of Science And Technology The University Of Tokyo
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