Oral Intake of Soy Isoflavone Aglycone Improves the Aged Skin of Adult Women
スポンサーリンク
概要
- 論文の詳細を見る
A double-blind, placebo-controlled trial was conducted to clinically evaluate the effect of soy isoflavone aglycone on the aged skin of middle-aged women. Twenty-six women volunteers in their late 30s and early 40s were randomly assigned to receive either a test food (13 women, the test food group) or a placebo food (13 women, the control group). These groups were given the test food (40 mg of soy isoflavone aglycone per day) and placebo, respectively, for 12 wk. The extent of linear and fine wrinkles at the lateral angle of the eyes was selected as the major evaluation criterion to assess the effects of foods, and the wrinkles' area ratio was used as the evaluation parameter. The extent of skin microrelief at the lateral angle of eyes and that of malar skin elasticity were used as secondary evaluation criteria, and the skin microrelief's area ratio and recovery of skin elasticity were used as the respective evaluation parameters. These parameters were assessed 4, 8, and 12 wk after the start of the test food or placebo intake. The test food group showed a statistically significant improvement of fine wrinkles at week 12 (p<0.05) and of malar skin elasticity at week 8 (p<0.05), compared with the control group. Although there was no significant difference between the test food group and the control group regarding effects on skin microrelief at lateral angle of the eyes, a significant intragroup improvement was observed at week 8 in the test food group (p<0.05). As for the test food safety, none of the subjects presented adverse symptoms during the study period or discontinued the intake of the test food. These data indicate that the oral intake of 40 mg soy isoflavone aglycones per day improves the aged skin of middle-aged women.
著者
-
OBATA Akio
Research and Development Division, Kikkoman Corporation
-
SAITO Makoto
Research and Development Division, Kikkoman Corporation
-
MATSUYAMA Asahi
Research and Development Division, Kikkoman Corporation
-
YAMAGUCHI HIDEYO
Institute of Medical Mycology, Teikyo University
-
Saito Makoto
Research And Development Division Kikkoman Corporation
-
Arii Masayuki
Research And Development Division Kikkoman Corporation
-
Saito M
Department Of Biotechnology And Life Science Tokyo University Of Agriculture And Technology
-
IZUMI Toru
Research and Development Division, Kikkoman Corporation
-
Obata A
Kikkoman Corp. Chiba Jpn
-
Obata Akio
Research & Development Division Kikkoman Corporation
-
Saito M
Research And Development Division Kikkoman Corporation
-
Matsuyama Asahi
Research And Development Division Kikkoman Corporation
-
Izumi Toru
Research And Development Division Kikkoman Corporation
-
Saito Makoto
Research & Development Division Kikkoman Corporation
-
Yamaguchi Hideyo
Institute Of Medical Mycology Teikyo University
-
Yamaguchi Hideyo
Institute Of Medical Mycology And Genome Research Center Teikyo University
関連論文
- A Comprehensive Gene Expression Analysis Toward the Understanding of Growth and Differentiation of Tobacco BY-2 Cells
- Cytotoxicity of Extracts from Alternaria alternata against Cultured Tobacco BY-2 Cells
- Distinctive Effects of Menadione on the In Vivo Catalase Activity and the Adaptation to Hydrogen Peroxide Stress in Yeast Cells
- PURIFICATION OF CHITINASE FROM TOBACCO CULTURED CELL BY-2
- QUANTITATIVE APPLICATION OF ELECTRIC STIMULUS BY THE SINGLE-CELL METHOD
- Intracellular Fate of 2-NBDG, a Fluorescent Probe for Glucose Uptake Activity, in Escherichia coli Cells
- Cell-lytic Activity of Tobacco BY-2 Induced by a Fungal Elicitor from Alternaria alternata Attributed to the Expression of a Class I β-1, 3-Glucanase Gene
- Isolation of a Novel Isozyme of Tobacco BY-2 Chitinase Induced by a Fungal Elicitor
- Effects of High Pressure Treatment on the Ultrastructure and Solubilization of Isolated Myofibrils(Food & Nutrition)
- Oral Intake of Soy Isoflavone Aglycone Improves the Aged Skin of Adult Women
- Antihypertensive and Natriuretic Effects of Less-Sodium Soy Sauce Containing γ-Aminobutyric Acid in Spontaneously Hypertensive Rats
- Safety Evaluation of Flavonoids-Containing Tomato Skin Extract
- Minimum-Energy State of an Axisymmetric Toroidal Plasma
- Complete Regression of Mouse Mammary Carcinoma with a Size Greater than 15 mm by Frequent Repeated Hyperthermia Using Magnetite Nanoparticles
- Application of an Aspergillus saitoi Protease Preparation to Soybean Curd to Modify Its Functional and Rheological Properties
- タバコ培養細胞細胞間膜への定量的傷害印加のための微小電極システムの応用
- Genotoxicity Studies of Fermented Soybean Extract
- Synthesis of 4-Hydroxy-3(2H)-furanone Acyl Derivatives and Their Anti-cataract Effect on Spontaneous Cataract Rats (ICR/f)
- Antioxidative Activities of 4-Hydroxy-3 (2H)-furanones and Their Anti-cataract Effect on Spontaneous Cataract Rat (ICR/f)
- Simultaneous Imaging of Multiple Fluorescent Probes in Bio-Cells
- An Evaluation of the Clinical Efficacy of Tomato Extract for Perennial Allergic Rhinitis
- Anti-Tumor Activities of the Antlered Form of Ganoderma lucidum in Allogeneic and Syngeneic Tumor-Bearing Mice
- Characteristics of Serine Acetyltransferase from Escherichia coli Deleting Different Lengths of Amino Acid Residues from the C-Terminus
- Effects of Bienzyme Complex Formation of Cysteine Synthetase from Escherichia coli on Some Properties and Kinetics
- 電気的シグナルによるイネ単一細胞内へのCa〔2+〕流入の制御
- CONTROL OF CALCIUM INFLUX INTO A SINGLE RICE CELL WITH AN ELECTRIC SIGNAL
- Automatic Mapping of Viable Microbial Cells Distributed in the Surface Layer of Cotton Fabrics
- Anti-allergic Activity of Naringenin Chalcone from a Tomato Skin Extract
- Viable Cell Detection by the Combined Use of Fluorescent Glucose and Fluorescent Glycine(Food & Nutrition Sience)
- ISOLATION AND ANALYSIS OF TOBACCO CULTURED CELL BY-2 CHITINASE (TBC)
- Total Syntheses of All Four Stereoisomers of Piscidic Acid via Catalytic Asymmetric Dihydroxylation of (Z)- and (E)-trisubstituted Olefins
- Total Synthesis of (+)-(2S, 3R)-Piscidic Acid via Catalytic Asymmetric Dihydroxylation of a Trisubstituted Olefin
- タバコ培養細胞における膜電位制御と膜インピーダンスの同時計測
- Effects of High Pressure Treatment on Ca^ Release and Ca^ Uptake of Sarcoplasmic Reticulum
- Pressure-induced Ca^ Release from Rabbit Sarcoplasmic Reticulum
- Effect of High Pressure Treatment on the Ultrastructure and Myofibrillar Protein of Beef Skeletal Muscle(Food & Nutrition)
- Functional Analysis of a Rice Putative Voltage-Dependent Ca^ Channel, OsTPC1, Expressed in Yeast Cells Lacking its Homologous Gene CCH1
- Lowering Effect of an Isoflavone-Rich Fermented Soybean Extract on the Serum Cholesterol Concentrations in Female Rats, with or without Ovariectomy, but Not in Male Rats
- Lack of an Inducible Effect of Dietary Soy Isoflavones on the mRNA Abundance of Hepatic Cytochrome P-450 Isozymes in Rats
- Clinical Efficacy of Halophilic Lactic Acid Bacterium Tetragenococcus halophilus Th221 from Soy Sauce Moromi for Perennial Allergic Rhinitis
- Rapid identification of Trichophyton tonsurans by specific PCR based on DNA sequences of nuclear ribosomal internal transcribed spacer (ITS) 1 region
- An Efficient Preparation of Acetyl Isoflavone Glucoside
- Single-Cell Imaging of the Ca^2+ Influx into Bovine Endothelial Cells Occurring in Response to an Alternating Electric
- Comprehensive Analysis of Glucan Elicitor-Regulated Gene Expression in Tobacco BY-2 Cells Reveals a Novel MYB Transcription Factor Involved in the Regulation of Phenylpropanoid Metabolism
- A One-Enzyme PCR-RFLP Assay for Identification of Six Medically Important Candida Species
- Beneficial Effects of Grape Seed Extract on Malondialdehyde-Modified LDL
- ANALYSIS OF RICE CHITINASE GENE EXPRESSION USING GFP REPORTER GENE
- ELECTRIC CONTROL OF INTERCELLULAR TRANSLOCATION OF A FLUOROCHOME IN PLANT CELLS.
- Decrease in the Gel Strength of Tofu Caused by an Enzyme Reaction during Soybean Grinding and Its Control
- Degradation of Sulfhydryl Groups in Soymilk by Lipoxygenases during Soybean Grinding
- CHITINASE GENE EXPRESSION BY VARIOUS STIMULI AND ANALYSIS OF INTERCELLULAR SIGNAL TRANSLOCATION IN RICE LEAF
- THE ESTABLISHMENT OF A NEW BIOLOGICAL ASSAY SYSTEM FOR SIMULTANEOUS MEASUREMENT OF BONE RESORPTION AND BONE MINERALIZATION IN ORGAN CULTURES OF CHICK EMBRYONIC FEMUR
- Antihypertensive and Natriuretic Effects of Less-Sodium Soy Sauce Containing γ-Aminobutyric Acid in Spontaneously Hypertensive Rats
- Application of an Aspergillus saitoi Protease Preparation to Soybean Curd to Modify Its Functional and Rheological Properties
- Evidence for the plasma membrane localization of a putative voltage-dependent Ca^ channel, OsTPC1, in rice
- Carotenoid Components in Soybean Seeds Varying with Seed Color and Maturation Stage
- Emulsifying and Oil-binding Properties of Bovine Serum Albumin and Its Enzymatic Hydrolyzate
- Purification and Characterization of Serine Acetyltransferase from Escherichia coli Partially Truncated at the C-Terminal Region
- Electroless Copper Deposition Using Fe(II) Complex as a Reducing Agent
- Naringenin Chalcone Suppresses Allergic Asthma by Inhibiting the Type-2 Function of CD4 T Cells
- Novel Histamine Measurement by HPLC Analysis Used to Assay Histidine Decarboxylase Inhibitory Activity of Shoyuflavones from Soy Sauce
- Paleoecological and Paleoenvironmental Changes in Lagoon Notoro-Ko (Japan) during the Last 200 Years Based on Diatom Assemblages and Sediment Chemistry(Earth Surface Processes, Natural Disasters and Historical Environmental Changes)
- Paleoecological and Paleoenvironmental Changes in Lagoon Notoro-Ko (Japan) during the Last 200 Years Based on Diatom Assemblages and Sediment Chemistry
- Metabolite profiling of soy sauce using gas chromatography with time-of-flight mass spectrometry and analysis of correlation with quantitative descriptive analysis(BREWING AND FOOD TECHNOLOGY)
- Anti-Influenza Virus Effects of Elderberry Juice and Its Fractions
- Cobalt-free Materials for Nickel-metal Hydride Battery: Self-discharge Suppression and Overdischarge-resistance Improvement
- Metabolite profiling of soy sauce using gas chromatography with time-of-flight mass spectrometry and analysis of correlation with quantitative descriptive analysis